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FB:cact
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | cact ( synonyms: 5848, BG:DS02740.15, CACT, CG5848, Cact, Cactus, NF-kappa-B inhibitor cactus, cac, dip6, female-sterile-(2)-ltoRN48, fs(2)ltoRN48, n(2)k17003 ) | |
| Protein Name(s) | cactus, | |
| External Links | ||
| FB | FBgn0000250 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
FB:FBrf0123082 |
IPI: Inferred from Physical Interaction |
FB:FBgn0024222 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0102368 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0141281 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0156690 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0179043 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0127230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0134783 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006967 |
positive regulation of antifungal peptide biosynthetic process |
FB:FBrf0110270 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006974 |
response to DNA damage stimulus |
FB:FBrf0208272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0200690 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0179043 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0009620 |
response to fungus |
FB:FBrf0132053 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009950 |
dorsal/ventral axis specification |
FB:FBrf0127230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009950 |
dorsal/ventral axis specification |
FB:FBrf0141281 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009950 |
dorsal/ventral axis specification |
FB:FBrf0193565 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019730 |
antimicrobial humoral response |
FB:FBrf0102368 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0019732 |
antifungal humoral response |
FB:FBrf0090665 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031594 |
neuromuscular junction |
FB:FBrf0155887 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0042308 |
negative regulation of protein import into nucleus |
FB:FBrf0156690 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0042994 |
cytoplasmic sequestering of transcription factor |
FB:FBrf0112152 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0045087 |
innate immune response |
FB:FBrf0188361 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046843 |
dorsal appendage formation |
FB:FBrf0054123 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0054123 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kim YS et al. (2000) Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells. J Biol Chem 275: 2071-9 PubMed GONUTS page
- ↑ 2.0 2.1 Nicolas E et al. (1998) In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila. J Biol Chem 273: 10463-9 PubMed GONUTS page
- ↑ 3.0 3.1 Lall S & Patel NH (2001) Conservation and divergence in molecular mechanisms of axis formation. Annu Rev Genet 35: 407-37 PubMed GONUTS page
- ↑ 4.0 4.1 Leclerc V & Reichhart JM (2004) The immune response of Drosophila melanogaster. Immunol Rev 198: 59-71 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 6.0 6.1 Meister M et al. (2000) The antimicrobial host defense of Drosophila. Curr Top Microbiol Immunol 248: 17-36 PubMed GONUTS page
- ↑ Schneider D (2000) Using Drosophila as a model insect. Nat Rev Genet 1: 218-26 PubMed GONUTS page
- ↑ Manfruelli P et al. (1999) A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. EMBO J 18: 3380-91 PubMed GONUTS page
- ↑ Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
- ↑ Koizumi K et al. (2007) RNA interference screen to identify genes required for Drosophila embryonic nervous system development. Proc Natl Acad Sci U S A 104: 5626-31 PubMed GONUTS page
- ↑ Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
- ↑ Medzhitov R & Janeway Jr C (2000) Fly immunity: great expectations. Genome Biol 1: REVIEWS106 PubMed GONUTS page
- ↑ Chen LY et al. (2006) Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo. Curr Biol 16: 1183-93 PubMed GONUTS page
- ↑ Lemaitre B et al. (1996) The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-83 PubMed GONUTS page
- ↑ Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ Bolatto C et al. (2003) Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila. J Neurobiol 54: 525-36 PubMed GONUTS page
- ↑ Ashburner M et al. (1999) An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics 153: 179-219 PubMed GONUTS page
- ↑ Kwiatkowski DP (2005) The complexity of genetic variation in a simple immune system. Trends Genet 21: 197-9 PubMed GONUTS page
- ↑ 19.0 19.1 Schüpbach T & Wieschaus E (1991) Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 129: 1119-36 PubMed GONUTS page
