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FB:br
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | br ( synonyms: 2B5, 2Bc, A18, BR, BR-C, BR-C Z1, BR-c, BRC, BRC-Z1, BRC-Z2, BRC-Z3, BRC-Z4, BR_C, Br, Br-C, Br-C Z2, Br-C-Z3, Br-Z4, BrC-Z1, Broad, Broad Complex, Broad complex, Broad-Complex, Broad-complex, CG11491, CG11511, CG11514, EG:123F11.1, EG:17A9.1, EG:25D2.1, PP1, PP2, Z1, Z2, Z3, Z4, br-C, br-Z1, br-Z3, broad complex, broad-complex, de12, ecdysone-sensitivity, ecs, l(1)2Ba, l(1)2Bab, l(1)2Bad, l(1)2Bb, l(1)2Bc, l(1)2Bd, l(1)ESHS5, l(1)G0018, l(1)G0042, l(1)G0284, l(1)G0284a, l(1)G0318, l(1)G0401, l(1)PP1, l(1)d norm-12, l(1)d.norm.1, l(1)dn1, l(1)n34, l(1)npr-1, l(1)npr1, l(1)pp-1, l(1)pp-2, l(1)pp1, l(1)pp2, l(1)ts132, l(1)ts144, l(1)ts358, l(1)ts376, lethal(1)2Bab, lethal(1)2Bc, lethal(1)2Bd, lethal(1)discs normal, lethal(1)non-pupariating-1, non-pupariating, non-pupariating-1, npr, npr-1, npr1, nprl, nrp, nrp1, o.c.c., overlapping-complementation-complex, rbp, rdp, rds, reduced bristles on palps, reduced palps, unequal wings, uq ) | |
| Protein Name(s) | broad, | |
| External Links | ||
| FB | FBgn0000210 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
FB:FBrf0091039 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0001752 |
compound eye photoreceptor fate commitment |
FB:FBrf0131261 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0155473 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0137174 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0124196 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0136571 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0146208 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0200192 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0124196 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0136571 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006914 |
autophagy |
FB:FBrf0134571 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0103241 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0131261 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007552 |
metamorphosis |
FB:FBrf0124196 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007552 |
metamorphosis |
FB:FBrf0128665 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007552 |
metamorphosis |
FB:FBrf0136571 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007562 |
eclosion |
FB:FBrf0155473 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0008219 |
cell death |
FB:FBrf0137172 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0009608 |
response to symbiont |
FB:FBrf0144807 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010629 |
negative regulation of gene expression |
FB:FBrf0200192 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035070 |
salivary gland histolysis |
FB:FBrf0128149 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035070 |
salivary gland histolysis |
FB:FBrf0146208 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0035071 |
salivary gland cell autophagic cell death |
FB:FBrf0126529 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0035072 |
ecdysone-mediated induction of salivary gland cell autophagic cell death |
FB:FBrf0133206 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0035075 |
response to ecdysone |
FB:FBrf0146965 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035193 |
larval central nervous system remodeling |
FB:FBrf0154749 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040034 |
regulation of development, heterochronic |
FB:FBrf0141454 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040034 |
regulation of development, heterochronic |
FB:FBrf0208858 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0091039 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0167375 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0190778 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048747 |
muscle fiber development |
FB:FBrf0190139 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003900 |
P |
From FB |
||
| GO:0048747 |
muscle fiber development |
FB:FBrf0190139 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0011656 |
P |
From FB |
||
| GO:0048808 |
male genitalia morphogenesis |
FB:FBrf0190778 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0071390 |
cellular response to ecdysone |
FB:FBrf0167375 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Crossgrove K et al. (1996) The Drosophila Broad-Complex early gene directly regulates late gene transcription during the ecdysone-induced puffing cascade. Dev Biol 180: 745-58 PubMed GONUTS page
- ↑ 2.0 2.1 Brennan CA et al. (2001) Broad-complex, but not ecdysone receptor, is required for progression of the morphogenetic furrow in the Drosophila eye. Development 128: 1-11 PubMed GONUTS page
- ↑ 3.0 3.1 Chen L et al. (2002) Control of Dopa decarboxylase gene expression by the Broad-Complex during metamorphosis in Drosophila. Mech Dev 119: 145-56 PubMed GONUTS page
- ↑ Gibson MC & Schubiger G (2001) Drosophila peripodial cells, more than meets the eye? Bioessays 23: 691-7 PubMed GONUTS page
- ↑ 5.0 5.1 Ward EJ et al. (2006) Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types. Dev Biol 297: 461-70 PubMed GONUTS page
- ↑ Lee CY & Baehrecke EH (2001) Steroid regulation of autophagic programmed cell death during development. Development 128: 1443-55 PubMed GONUTS page
- ↑ Brennan CA et al. (1998) Ecdysone pathway is required for furrow progression in the developing Drosophila eye. Development 125: 2653-64 PubMed GONUTS page
- ↑ Tissot M & Stocker RF (2000) Metamorphosis in drosophila and other insects: the fate of neurons throughout the stages. Prog Neurobiol 62: 89-111 PubMed GONUTS page
- ↑ Thummel CS (2001) Steroid-triggered death by autophagy. Bioessays 23: 677-82 PubMed GONUTS page
- ↑ Sorrentino RP et al. (2002) Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated. Dev Biol 243: 65-80 PubMed GONUTS page
- ↑ Jiang C et al. (2000) A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis. Mol Cell 5: 445-55 PubMed GONUTS page
- ↑ Buszczak M & Segraves WA (2000) Insect metamorphosis: out with the old, in with the new. Curr Biol 10: R830-3 PubMed GONUTS page
- ↑ Sempere LF et al. (2002) The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster. Dev Biol 244: 170-9 PubMed GONUTS page
- ↑ Thummel CS (2001) Molecular mechanisms of developmental timing in C. elegans and Drosophila. Dev Cell 1: 453-65 PubMed GONUTS page
- ↑ Parrish JZ et al. (2009) The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron 63: 788-802 PubMed GONUTS page
- ↑ 16.0 16.1 Daish TJ et al. (2003) Distinct promoter regions regulate spatial and temporal expression of the Drosophila caspase dronc. Cell Death Differ 10: 1348-56 PubMed GONUTS page
- ↑ 17.0 17.1 Wilson TG et al. (2006) Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex. Genetics 172: 253-64 PubMed GONUTS page
- ↑ 18.0 18.1 Lovato TL et al. (2005) Transcription of Myocyte enhancer factor-2 in adult Drosophila myoblasts is induced by the steroid hormone ecdysone. Dev Biol 288: 612-21 PubMed GONUTS page
