Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:botv

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) botv ( synonyms: BcDNA:LD21192, Botv, Brother of tout-velu, CG15110, DEXT3, DEXTL3, Dextl3, Drosophila Ext-like 3, Extl3, brother of tout velu, brother-of-tout-velu )
Protein Name(s) brother of tout-velu,
External Links
FB FBgn0027535

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001888

glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

FB:FBrf0184305

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q9UBQ6

F

From FB

GO:0005783

endoplasmic reticulum

FB:FBrf0174560
PMID:14998928[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005794

Golgi apparatus

FB:FBrf0174560
PMID:14998928[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006024

glycosaminoglycan biosynthetic process

FB:FBrf0174560
PMID:14998928[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006044

N-acetylglucosamine metabolic process

FB:FBrf0184305

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q9UBQ6

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0167537
PMID:14645127[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0174560
PMID:14998928[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0134246

NAS: Non-traceable Author Statement

P

From FB

GO:0008101

decapentaplegic signaling pathway

FB:FBrf0167537
PMID:14645127[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008101

decapentaplegic signaling pathway

FB:FBrf0174560
PMID:14998928[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008375

acetylglucosaminyltransferase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF089748

F

From FB

GO:0008375

acetylglucosaminyltransferase activity

FB:FBrf0149597
PMID:11832488[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0008375

acetylglucosaminyltransferase activity

FB:FBrf0155642
PMID:12464307[4]

NAS: Non-traceable Author Statement

F

From FB

GO:0015012

heparan sulfate proteoglycan biosynthetic process

FB:FBrf0149597
PMID:11832488[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0015012

heparan sulfate proteoglycan biosynthetic process

FB:FBrf0155642
PMID:12464307[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0015012

heparan sulfate proteoglycan biosynthetic process

FB:FBrf0190890
PMID:16303756[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0015014

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

FB:FBrf0147384

NAS: Non-traceable Author Statement

P

From FB

GO:0015014

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

FB:FBrf0167537
PMID:14645127[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016021

integral to membrane

FB:FBrf0149597
PMID:11832488[3]

ISM: Inferred from Sequence Model

C

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0167537
PMID:14645127[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0174560
PMID:14998928[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031227

intrinsic to endoplasmic reticulum membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015338

C

From FB

GO:0042328

heparan sulfate N-acetylglucosaminyltransferase activity

FB:FBrf0147384

NAS: Non-traceable Author Statement

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Han C et al. (2004) Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development 131: 1563-75 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Takei Y et al. (2004) Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development 131: 73-82 PubMed GONUTS page
  3. 3.0 3.1 3.2 Kim BT et al. (2002) Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation. J Biol Chem 277: 13659-65 PubMed GONUTS page
  4. 4.0 4.1 Wilson IB (2002) Glycosylation of proteins in plants and invertebrates. Curr Opin Struct Biol 12: 569-77 PubMed GONUTS page
  5. Izumikawa T et al. (2006) Heparan sulfate polymerization in Drosophila. J Biol Chem 281: 1929-34 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox