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FB:boss

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) boss ( synonyms: BOSS, Bos, Boss, Bride of Sevenless, Bride of sevenless, CG8285, F, F transcript, X55887 )
Protein Name(s) bride of sevenless,
External Links
FB FBgn0000206

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004888

transmembrane signaling receptor activity

FB:FBrf0129744
PMID:10908591[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004930

G-protein coupled receptor activity

FB:FBrf0152099
PMID:12163486[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004930

G-protein coupled receptor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR017978

F

From FB

GO:0005102

receptor binding

FB:FBrf0159232
PMID:12612640[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0005118

sevenless binding

FB:FBrf0054769
PMID:1857416[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0003366

F

From FB

GO:0005118

sevenless binding

FB:FBrf0054769
PMID:1857416[4]

IPI: Inferred from Physical Interaction

FB:FBgn0003366

F

From FB

GO:0005118

sevenless binding

FB:FBrf0123791

NAS: Non-traceable Author Statement

F

From FB

GO:0005771

multivesicular body

FB:FBrf0054769
PMID:1857416[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0105495

NAS: Non-traceable Author Statement

C

From FB

GO:0005887

integral to plasma membrane

FB:FBrf0059124
PMID:7680109[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0007165

signal transduction

FB:FBrf0129744
PMID:10908591[1]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007186

G-protein coupled receptor signaling pathway

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR017978

P

From FB

GO:0007465

R7 cell fate commitment

FB:FBrf0129916
PMID:10929403[6]

TAS: Traceable Author Statement

P

From FB

GO:0007601

visual perception

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002956

P

From FB

GO:0009749

response to glucose stimulus

FB:FBrf0205989
PMID:18832180[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016021

integral to membrane

FB:FBrf0123791

NAS: Non-traceable Author Statement

C

From FB

GO:0016021

integral to membrane

FB:FBrf0129744
PMID:10908591[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0016021

integral to membrane

FB:FBrf0159232
PMID:12612640[3]

NAS: Non-traceable Author Statement

C

From FB

GO:0030297

transmembrane receptor protein tyrosine kinase activator activity

FB:FBrf0059124
PMID:7680109[5]

IDA: Inferred from Direct Assay

F

From FB

GO:0031528

microvillus membrane

FB:FBrf0054769
PMID:1857416[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0042593

glucose homeostasis

FB:FBrf0205989
PMID:18832180[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045466

R7 cell differentiation

FB:FBrf0144824
PMID:11880339[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0045467

R7 cell development

FB:FBrf0144824
PMID:11880339[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0045470

R8 cell-mediated photoreceptor organization

FB:FBrf0144824
PMID:11880339[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0045500

sevenless signaling pathway

FB:FBrf0123791

NAS: Non-traceable Author Statement

P

From FB

GO:0048749

compound eye development

FB:FBrf0123791

NAS: Non-traceable Author Statement

P

From FB

GO:0050730

regulation of peptidyl-tyrosine phosphorylation

FB:FBrf0059124
PMID:7680109[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0055088

lipid homeostasis

FB:FBrf0205989
PMID:18832180[7]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Brody T & Cravchik A (2000) Drosophila melanogaster G protein-coupled receptors. J Cell Biol 150: F83-8 PubMed GONUTS page
  2. Radford JC et al. (2002) Systematic G-protein-coupled receptor analysis in Drosophila melanogaster identifies a leucokinin receptor with novel roles. J Biol Chem 277: 38810-7 PubMed GONUTS page
  3. 3.0 3.1 González-Gaitán M (2003) Signal dispersal and transduction through the endocytic pathway. Nat Rev Mol Cell Biol 4: 213-24 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Krämer H et al. (1991) Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor. Nature 352: 207-12 PubMed GONUTS page
  5. 5.0 5.1 5.2 Hart AC et al. (1993) Extracellular domain of the boss transmembrane ligand acts as an antagonist of the sev receptor. Nature 361: 732-6 PubMed GONUTS page
  6. Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
  7. 7.0 7.1 7.2 Kohyama-Koganeya A et al. (2008) A Drosophila orphan G protein-coupled receptor BOSS functions as a glucose-responding receptor: loss of boss causes abnormal energy metabolism. Proc Natl Acad Sci U S A 105: 15328-33 PubMed GONUTS page
  8. 8.0 8.1 8.2 Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
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