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FB:bnl

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) bnl ( synonyms: Bnl, Branchless, CG4608, DFGF, DmBnl, FGF, Fibroblast Growth Factor, fibroblast growth factor, l(3)06916, l(3)neo52 )
Protein Name(s) branchless,
External Links
FB FBgn0014135

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000187

activation of MAPK activity

FB:FBrf0147141
PMID:12175485[1]

IEP: Inferred from Expression Pattern

P

From FB

GO:0001763

morphogenesis of a branching structure

FB:FBrf0131240
PMID:11063940[2]

TAS: Traceable Author Statement

P

From FB

GO:0005104

fibroblast growth factor receptor binding

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:1099809

F

From FB

GO:0005104

fibroblast growth factor receptor binding

FB:FBrf0121140

NAS: Non-traceable Author Statement

F

From FB

GO:0005104

fibroblast growth factor receptor binding

FB:FBrf0129696
PMID:10943305[3]

TAS: Traceable Author Statement

F

From FB

GO:0005104

fibroblast growth factor receptor binding

FB:FBrf0130167
PMID:11128983[4]

TAS: Traceable Author Statement

F

From FB

GO:0005104

fibroblast growth factor receptor binding

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

F

From FB

GO:0005104

fibroblast growth factor receptor binding

FB:FBrf0179928
PMID:15475116[6]

TAS: Traceable Author Statement

F

From FB

GO:0005576

extracellular region

FB:FBrf0091184
PMID:8978613[7]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005576

extracellular region

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0006935

chemotaxis

FB:FBrf0130167
PMID:11128983[4]

TAS: Traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0130167
PMID:11128983[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0160886
PMID:12885551[8]

TAS: Traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0190302
PMID:16481357[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007426

tracheal outgrowth, open tracheal system

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0125237
PMID:10684581[10]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0129696
PMID:10943305[3]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0144739
PMID:11835274[11]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0161023
PMID:12791296[12]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0168046
PMID:14624839[13]

TAS: Traceable Author Statement

P

From FB

GO:0007428

primary branching, open tracheal system

FB:FBrf0161023
PMID:12791296[12]

TAS: Traceable Author Statement

P

From FB

GO:0007428

primary branching, open tracheal system

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

P

From FB

GO:0007429

secondary branching, open tracheal system

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

P

From FB

GO:0007430

terminal branching, open tracheal system

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

P

From FB

GO:0008083

growth factor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002209
InterPro:IPR002348

F

From FB

GO:0008543

fibroblast growth factor receptor signaling pathway

FB:FBrf0129696
PMID:10943305[3]

TAS: Traceable Author Statement

P

From FB

GO:0008543

fibroblast growth factor receptor signaling pathway

FB:FBrf0144739
PMID:11835274[11]

NAS: Non-traceable Author Statement

P

From FB

GO:0008543

fibroblast growth factor receptor signaling pathway

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

P

From FB

GO:0008543

fibroblast growth factor receptor signaling pathway

FB:FBrf0179928
PMID:15475116[6]

TAS: Traceable Author Statement

P

From FB

GO:0035152

regulation of tube architecture, open tracheal system

FB:FBrf0161023
PMID:12791296[12]

TAS: Traceable Author Statement

P

From FB

GO:0035215

genital disc development

FB:FBrf0148926
PMID:12062107[14]

IEP: Inferred from Expression Pattern

P

From FB

GO:0035231

cytoneme assembly

FB:FBrf0109017
PMID:10367889[15]

IDA: Inferred from Direct Assay

P

From FB

GO:0046847

filopodium assembly

FB:FBrf0148947
PMID:12015974[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050918

positive chemotaxis

FB:FBrf0129696
PMID:10943305[3]

TAS: Traceable Author Statement

P

From FB

GO:0050918

positive chemotaxis

FB:FBrf0145712

IDA: Inferred from Direct Assay

P

From FB

GO:0050918

positive chemotaxis

FB:FBrf0160886
PMID:12885551[8]

TAS: Traceable Author Statement

P

From FB

GO:0050918

positive chemotaxis

FB:FBrf0167264
PMID:14570584[5]

TAS: Traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Ohshiro T et al. (2002) Ligand-dependent activation of breathless FGF receptor gene in Drosophila developing trachea. Mech Dev 114: 3-11 PubMed GONUTS page
  2. Affolter M & Shilo BZ (2000) Genetic control of branching morphogenesis during Drosophila tracheal development. Curr Opin Cell Biol 12: 731-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Affolter M (2000) Cell-cell interaction during Drosophila embryogenesis: novel mechanisms and molecules. Ernst Schering Res Found Workshop 65-79 PubMed GONUTS page
  4. 4.0 4.1 4.2 Wilson R & Leptin M (2000) Fibroblast growth factor receptor-dependent morphogenesis of the Drosophila mesoderm. Philos Trans R Soc Lond B Biol Sci 355: 891-5 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  6. 6.0 6.1 Itoh N & Ornitz DM (2004) Evolution of the Fgf and Fgfr gene families. Trends Genet 20: 563-9 PubMed GONUTS page
  7. Sutherland D et al. (1996) branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 87: 1091-101 PubMed GONUTS page
  8. 8.0 8.1 Ribeiro C et al. (2003) Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Dev Biol 260: 1-8 PubMed GONUTS page
  9. Jarvis LA et al. (2006) Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases. Development 133: 1133-42 PubMed GONUTS page
  10. Zelzer E & Shilo BZ (2000) Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-26 PubMed GONUTS page
  11. 11.0 11.1 Rosin D & Shilo BZ (2002) Branch-specific migration cues in the Drosophila tracheal system. Bioessays 24: 110-3 PubMed GONUTS page
  12. 12.0 12.1 12.2 Uv A et al. (2003) Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems. Trends Cell Biol 13: 301-9 PubMed GONUTS page
  13. Nelson WJ (2003) Tube morphogenesis: closure, but many openings remain. Trends Cell Biol 13: 615-21 PubMed GONUTS page
  14. Ahmad SM & Baker BS (2002) Sex-specific deployment of FGF signaling in Drosophila recruits mesodermal cells into the male genital imaginal disc. Cell 109: 651-61 PubMed GONUTS page
  15. Ramírez-Weber FA & Kornberg TB (1999) Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 97: 599-607 PubMed GONUTS page
  16. Ribeiro C et al. (2002) In vivo imaging reveals different cellular functions for FGF and Dpp signaling in tracheal branching morphogenesis. Dev Cell 2: 677-83 PubMed GONUTS page
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