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FB:beta-Spec
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | beta-Spec ( synonyms: B-spec, Beta-spectrin, CG5870, SPEC8, Spec, Spec-beta, Specbeta, Spectrin, anon-EST:fe1B3, anon-fast-evolving-1B3, b spectrin, b-Spec, beta, beta spectrin, beta-Spectrin, beta-spec, beta-spectrin, betaSpec, betaspec, i168, i6, karussell, kus, l(1)G0074, l(1)G0108, l(1)G0198, spectrin ) | |
| Protein Name(s) | beta Spectrin, | |
| External Links | ||
| FB | FBgn0250788 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
FB:FBrf0124193 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0126673 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0152121 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005200 |
structural constituent of cytoskeleton |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005516 |
calmodulin binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005516 |
calmodulin binding |
FB:FBrf0124193 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005546 |
phosphatidylinositol-4,5-bisphosphate binding |
FB:FBrf0205087 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005811 |
lipid particle |
FB:FBrf0200342 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0191925 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0195180 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0210975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007009 |
plasma membrane organization |
FB:FBrf0131399 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007026 |
negative regulation of microtubule depolymerization |
FB:FBrf0187325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007274 |
neuromuscular synaptic transmission |
FB:FBrf0136992 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0211527 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007409 |
axonogenesis |
FB:FBrf0194635 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0106675 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008017 |
microtubule binding |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0008091 |
spectrin |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0008091 |
spectrin |
FB:FBrf0124193 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0008091 |
spectrin |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0008092 |
cytoskeletal protein binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0016199 |
axon midline choice point recognition |
FB:FBrf0191925 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016327 |
apicolateral plasma membrane |
FB:FBrf0141282 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0016328 |
lateral plasma membrane |
FB:FBrf0205087 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016328 |
lateral plasma membrane |
FB:FBrf0209342 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030424 |
axon |
FB:FBrf0191925 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030506 |
ankyrin binding |
FB:FBrf0211527 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0030721 |
spectrosome organization |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031594 |
neuromuscular junction |
FB:FBrf0201824 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0042062 |
long-term strengthening of neuromuscular junction |
FB:FBrf0187325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045169 |
fusome |
FB:FBrf0091300 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045170 |
spectrosome |
FB:FBrf0091300 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045170 |
spectrosome |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0045478 |
fusome organization |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048790 |
maintenance of presynaptic active zone structure |
FB:FBrf0192906 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0050807 |
regulation of synapse organization |
FB:FBrf0187325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051015 |
actin filament binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0072499 |
photoreceptor cell axon guidance |
FB:FBrf0212583 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Röper K et al. (2002) The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. J Cell Sci 115: 4215-25 PubMed GONUTS page
- ↑ 2.0 2.1 Das A et al. (2008) Unexpected complexity in the mechanisms that target assembly of the spectrin cytoskeleton. J Biol Chem 283: 12643-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Sisson JC et al. (2000) Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization. J Cell Biol 151: 905-18 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Garbe DS et al. (2007) beta-Spectrin functions independently of Ankyrin to regulate the establishment and maintenance of axon connections in the Drosophila embryonic CNS. Development 134: 273-84 PubMed GONUTS page
- ↑ Das A et al. (2006) Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. J Cell Biol 175: 325-35 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Pielage J et al. (2005) Presynaptic spectrin is essential for synapse stabilization. Curr Biol 15: 918-28 PubMed GONUTS page
- ↑ Featherstone DE et al. (2001) Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release. J Neurosci 21: 4215-24 PubMed GONUTS page
- ↑ 8.0 8.1 Mazock GH et al. (2010) Transgene rescue identifies an essential function for Drosophila beta spectrin in the nervous system and a selective requirement for ankyrin-2-binding activity. Mol Biol Cell 21: 2860-8 PubMed GONUTS page
- ↑ Hülsmeier J et al. (2007) Distinct functions of alpha-Spectrin and beta-Spectrin during axonal pathfinding. Development 134: 713-22 PubMed GONUTS page
- ↑ Hummel T et al. (1999) Commissure formation in the embryonic CNS of Drosophila. Development 126: 771-9 PubMed GONUTS page
- ↑ 11.0 11.1 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ Tepass U et al. (2001) Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet 35: 747-84 PubMed GONUTS page
- ↑ Chen TW et al. (2009) Membrane domain modulation by Spectrins in Drosophila photoreceptor morphogenesis. Genesis 47: 744-50 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ Kohsaka H et al. (2007) In vivo induction of postsynaptic molecular assembly by the cell adhesion molecule Fasciclin2. J Cell Biol 179: 1289-300 PubMed GONUTS page
- ↑ 16.0 16.1 de Cuevas M et al. (1996) alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary. Development 122: 3959-68 PubMed GONUTS page
- ↑ Pielage J et al. (2006) A postsynaptic spectrin scaffold defines active zone size, spacing, and efficacy at the Drosophila neuromuscular junction. J Cell Biol 175: 491-503 PubMed GONUTS page
- ↑ Ohler S et al. (2011) Hts, the Drosophila homologue of Adducin, physically interacts with the transmembrane receptor Golden goal to guide photoreceptor axons. Dev Dyn 240: 135-48 PubMed GONUTS page
