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FB:ato

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ato ( synonyms: ATO, At, Ato, Atonal, CG7508, ato1, atona, bHLHa10 )
Protein Name(s) atonal,
External Links
FB FBgn0010433

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000187

activation of MAPK activity

FB:FBrf0144824
PMID:11880339[1]

TAS: Traceable Author Statement

P

From FB

GO:0001745

compound eye morphogenesis

FB:FBrf0126773
PMID:10704398[2]

TAS: Traceable Author Statement

P

From FB

GO:0001746

Bolwig's organ morphogenesis

FB:FBrf0126773
PMID:10704398[2]

IEP: Inferred from Expression Pattern

P

From FB

GO:0001748

optic lobe placode development

FB:FBrf0108690
PMID:10357938[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0124094

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0078301

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0124094

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0078301

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0124094

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0180539
PMID:15485919[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0124094

NAS: Non-traceable Author Statement

P

From FB

GO:0007173

epidermal growth factor receptor signaling pathway

FB:FBrf0127389
PMID:10725244[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0003731

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0127389
PMID:10725244[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0004644

P

From FB

GO:0007399

nervous system development

FB:FBrf0083410
PMID:8060613[6]

TAS: Traceable Author Statement

P

From FB

GO:0007399

nervous system development

FB:FBrf0124094

NAS: Non-traceable Author Statement

P

From FB

GO:0007420

brain development

FB:FBrf0127108
PMID:10774724[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0144824
PMID:11880339[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0007423

sensory organ development

FB:FBrf0124094

NAS: Non-traceable Author Statement

P

From FB

GO:0007423

sensory organ development

FB:FBrf0151529
PMID:12142008[8]

TAS: Traceable Author Statement

P

From FB

GO:0007423

sensory organ development

FB:FBrf0161619

TAS: Traceable Author Statement

P

From FB

GO:0007423

sensory organ development

FB:FBrf0179485
PMID:15273984[9]

TAS: Traceable Author Statement

P

From FB

GO:0007423

sensory organ development

FB:FBrf0193556
PMID:17260155[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007438

oenocyte development

FB:FBrf0148967
PMID:12050142[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007455

eye-antennal disc morphogenesis

FB:FBrf0192868
PMID:16963016[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007460

R8 cell fate commitment

FB:FBrf0073459
PMID:8196767[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007460

R8 cell fate commitment

FB:FBrf0124094

NAS: Non-traceable Author Statement

P

From FB

GO:0007460

R8 cell fate commitment

FB:FBrf0127389
PMID:10725244[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007605

sensory perception of sound

FB:FBrf0129796
PMID:10934246[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007605

sensory perception of sound

FB:FBrf0151906
PMID:12203727[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008038

neuron recognition

FB:FBrf0156020
PMID:12526771[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016330

second mitotic wave involved in compound eye morphogenesis

FB:FBrf0141762
PMID:11735386[17]

TAS: Traceable Author Statement

P

From FB

GO:0016360

sensory organ precursor cell fate determination

FB:FBrf0126761
PMID:10707972[18]

IDA: Inferred from Direct Assay

P

From FB

GO:0016360

sensory organ precursor cell fate determination

FB:FBrf0179899
PMID:15313555[19]

TAS: Traceable Author Statement

P

From FB

GO:0016360

sensory organ precursor cell fate determination

FB:FBrf0201152
PMID:17709231[20]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045165

cell fate commitment

FB:FBrf0108690
PMID:10357938[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045433

male courtship behavior, veined wing generated song production

FB:FBrf0138453
PMID:11529478[21]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045464

R8 cell fate specification

FB:FBrf0141762
PMID:11735386[17]

TAS: Traceable Author Statement

P

From FB

GO:0045464

R8 cell fate specification

FB:FBrf0144824
PMID:11880339[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0045465

R8 cell differentiation

FB:FBrf0155653
PMID:11861163[22]

TAS: Traceable Author Statement

P

From FB

GO:0045465

R8 cell differentiation

FB:FBrf0179485
PMID:15273984[9]

TAS: Traceable Author Statement

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0180539
PMID:15485919[4]

IEP: Inferred from Expression Pattern

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0180539
PMID:15485919[4]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0048666

neuron development

FB:FBrf0190556
PMID:16547170[23]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048800

antennal morphogenesis

FB:FBrf0146985
PMID:11934862[24]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048801

antennal joint morphogenesis

FB:FBrf0151906
PMID:12203727[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[23]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0000981

sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0180539
PMID:15485919[4]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
  2. 2.0 2.1 Suzuki T & Saigo K (2000) Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus. Development 127: 1531-40 PubMed GONUTS page
  3. 3.0 3.1 Daniel A et al. (1999) The control of cell fate in the embryonic visual system by atonal, tailless and EGFR signaling. Development 126: 2945-54 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Powell LM et al. (2004) The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites. Mol Cell Biol 24: 9517-26 PubMed GONUTS page
  5. 5.0 5.1 5.2 White NM & Jarman AP (2000) Drosophila atonal controls photoreceptor R8-specific properties and modulates both receptor tyrosine kinase and Hedgehog signalling. Development 127: 1681-9 PubMed GONUTS page
  6. Salzberg A et al. (1994) Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron 13: 269-87 PubMed GONUTS page
  7. Hassan BA et al. (2000) atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain. Neuron 25: 549-61 PubMed GONUTS page
  8. Skaer N et al. (2002) Gene duplication at the achaete-scute complex and morphological complexity of the peripheral nervous system in Diptera. Trends Genet 18: 399-405 PubMed GONUTS page
  9. 9.0 9.1 Treisman JE (2004) Coming to our senses. Bioessays 26: 825-8 PubMed GONUTS page
  10. Grillenzoni N et al. (2007) Role of proneural genes in the formation of the larval olfactory organ of Drosophila. Dev Genes Evol 217: 209-19 PubMed GONUTS page
  11. Brodu V et al. (2002) abdominal A specifies one cell type in Drosophila by regulating one principal target gene. Development 129: 2957-63 PubMed GONUTS page
  12. Brown KE et al. (2006) Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway. Dev Biol 300: 710-21 PubMed GONUTS page
  13. Jarman AP et al. (1994) Atonal is the proneural gene for Drosophila photoreceptors. Nature 369: 398-400 PubMed GONUTS page
  14. Eberl DF et al. (2000) Genetically similar transduction mechanisms for touch and hearing in Drosophila. J Neurosci 20: 5981-8 PubMed GONUTS page
  15. 15.0 15.1 Göpfert MC et al. (2002) atonal is required for exoskeletal joint formation in the Drosophila auditory system. Dev Dyn 225: 106-9 PubMed GONUTS page
  16. Zlatic M et al. (2003) Genetic specification of axonal arbors: atonal regulates robo3 to position terminal branches in the Drosophila nervous system. Neuron 37: 41-51 PubMed GONUTS page
  17. 17.0 17.1 Baker NE (2001) Cell proliferation, survival, and death in the Drosophila eye. Semin Cell Dev Biol 12: 499-507 PubMed GONUTS page
  18. Huang ML et al. (2000) The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. Neuron 25: 57-67 PubMed GONUTS page
  19. Hallem EA & Carlson JR (2004) The odor coding system of Drosophila. Trends Genet 20: 453-9 PubMed GONUTS page
  20. Maung SM & Jarman AP (2007) Functional distinctness of closely related transcription factors: a comparison of the Atonal and Amos proneural factors. Mech Dev 124: 647-56 PubMed GONUTS page
  21. Tauber E & Eberl DF (2001) Song production in auditory mutants of Drosophila: the role of sensory feedback. J Comp Physiol A 187: 341-8 PubMed GONUTS page
  22. Peters MA (2002) Patterning the neural retina. Curr Opin Neurobiol 12: 43-8 PubMed GONUTS page
  23. 23.0 23.1 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
  24. Dong PD et al. (2002) Distal-less and homothorax regulate multiple targets to pattern the Drosophila antenna. Development 129: 1967-74 PubMed GONUTS page
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