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FB:aret
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | aret ( synonyms: Aret, BcDNA:GM15173, Bru, Bruno, CG31762, CG6319, Dm Bru, NEST:bs01g04, NEST:bs34h11, aret/bruno1, arrest/Bruno, bru, bruno, ms(2)01284 ) | |
| Protein Name(s) | arrest, | |
| External Links | ||
| FB | FBgn0000114 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0000381 |
regulation of alternative nuclear mRNA splicing, via spliceosome |
FB:FBrf0180650 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0002121 |
inter-male aggressive behavior |
FB:FBrf0208496 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003723 |
RNA binding |
FB:FBrf0189903 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0086125 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0110978 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0129923 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0148886 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:2550 |
F |
From FB |
||
| GO:0003729 |
mRNA binding |
FB:FBrf0152348 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003730 |
mRNA 3'-UTR binding |
FB:FBrf0152348 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003730 |
mRNA 3'-UTR binding |
FB:FBrf0157198 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0107851 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015903 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0155723 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004882 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0180650 |
IC: Inferred by Curator |
GO:0000381 |
C |
From FB |
||
| GO:0006378 |
mRNA polyadenylation |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007281 |
germ cell development |
FB:FBrf0190220 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007286 |
spermatid development |
FB:FBrf0064394 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0086125 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0103246 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0152348 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0157336 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0189903 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0157198 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030727 |
germarium-derived female germ-line cyst formation |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031536 |
positive regulation of exit from mitosis |
FB:FBrf0190220 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042078 |
germ-line stem cell division |
FB:FBrf0132360 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0043186 |
P granule |
FB:FBrf0174811 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0046011 |
regulation of oskar mRNA translation |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0054123 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0135959 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0157198 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Park JW et al. (2004) Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci U S A 101: 15974-9 PubMed GONUTS page
- ↑ Edwards AC et al. (2009) Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol 7: 29 PubMed GONUTS page
- ↑ 3.0 3.1 Chekulaeva M et al. (2006) Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Cell 124: 521-33 PubMed GONUTS page
- ↑ van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
- ↑ Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Dean KA et al. (2002) Translational repressors in Drosophila. Trends Genet 18: 572-7 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Filardo P & Ephrussi A (2003) Bruno regulates gurken during Drosophila oogenesis. Mech Dev 120: 289-97 PubMed GONUTS page
- ↑ Lie YS & Macdonald PM (1999) Apontic binds the translational repressor Bruno and is implicated in regulation of oskar mRNA translation. Development 126: 1129-38 PubMed GONUTS page
- ↑ Castagnetti S & Ephrussi A (2003) Orb and a long poly(A) tail are required for efficient oskar translation at the posterior pole of the Drosophila oocyte. Development 130: 835-43 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ 11.0 11.1 Sugimura I & Lilly MA (2006) Bruno inhibits the expression of mitotic cyclins during the prophase I meiotic arrest of Drosophila oocytes. Dev Cell 10: 127-35 PubMed GONUTS page
- ↑ Castrillon DH et al. (1993) Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics 135: 489-505 PubMed GONUTS page
- ↑ Cooperstock RL & Lipshitz HD (1997) Control of mRNA stability and translation during Drosophila development. Semin Cell Dev Biol 8: 541-9 PubMed GONUTS page
- ↑ Johnstone O & Lasko P (2001) Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet 35: 365-406 PubMed GONUTS page
- ↑ Leatherman JL & Jongens TA (2003) Transcriptional silencing and translational control: key features of early germline development. Bioessays 25: 326-35 PubMed GONUTS page
- ↑ Snee MJ & Macdonald PM (2004) Live imaging of nuage and polar granules: evidence against a precursor-product relationship and a novel role for Oskar in stabilization of polar granule components. J Cell Sci 117: 2109-20 PubMed GONUTS page
- ↑ Schüpbach T & Wieschaus E (1991) Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 129: 1119-36 PubMed GONUTS page
- ↑ Parisi MJ et al. (2001) The arrest gene is required for germline cyst formation during Drosophila oogenesis. Genesis 29: 196-209 PubMed GONUTS page