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FB:aph-1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | aph-1 ( synonyms: Aph-1, CG2855, Dm APH-1, Pen-1, aph, aph1, dAph-1, l(2)23AB6, l(2)23Ag, pen-1, presenilin enhancer-1, presenilin stabilization factor ) | |
| Protein Name(s) | anterior pharynx defective 1, | |
| External Links | ||
| FB | FBgn0031458 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004175 |
endopeptidase activity |
FB:FBrf0151254 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0004175 |
endopeptidase activity |
FB:FBrf0157158 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0146570 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0151254 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0157158 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0151254 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0016485 |
protein processing |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0043085 |
positive regulation of catalytic activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Francis R et al. (2002) aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev Cell 3: 85-97 PubMed GONUTS page
- ↑ 2.0 2.1 Takasugi N et al. (2003) The role of presenilin cofactors in the gamma-secretase complex. Nature 422: 438-41 PubMed GONUTS page
