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FB:ap
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | ap ( synonyms: AP, APTEROUS, Ap, Apt, Apterous, CG8376, LIM, S-2a, Xa, Xasta, blt, no-wings, tornwing, trw ) | |
| Protein Name(s) | apterous, | |
| External Links | ||
| FB | FBgn0000099 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
FB:FBrf0106026 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123927 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0127419 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0212480 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006351 |
transcription, DNA-dependent |
FB:FBrf0127419 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006351 |
transcription, DNA-dependent |
FB:FBrf0127419 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0127419 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0158840 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0127419 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007450 |
dorsal/ventral pattern formation, imaginal disc |
FB:FBrf0151319 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007451 |
dorsal/ventral lineage restriction, imaginal disc |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007472 |
wing disc morphogenesis |
FB:FBrf0123927 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0151319 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007479 |
leg disc proximal/distal pattern formation |
FB:FBrf0131382 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007481 |
haltere disc morphogenesis |
FB:FBrf0123927 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0131298 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0151208 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007526 |
larval somatic muscle development |
FB:FBrf0212632 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007559 |
histolysis |
FB:FBrf0058455 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0123927 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0035218 |
leg disc development |
FB:FBrf0179395 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0036011 |
imaginal disc-derived leg segmentation |
FB:FBrf0179395 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045165 |
cell fate commitment |
FB:FBrf0138533 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0106026 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0190133 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0202749 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000242 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Benveniste RJ et al. (1998) Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor. Development 125: 4757-65 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 van Meyel DJ et al. (2000) Chip is an essential cofactor for apterous in the regulation of axon guidance in Drosophila. Development 127: 1823-31 PubMed GONUTS page
- ↑ Arber S & Caroni P (1996) Specificity of single LIM motifs in targeting and LIM/LIM interactions in situ. Genes Dev 10: 289-300 PubMed GONUTS page
- ↑ Skeath JB & Thor S (2003) Genetic control of Drosophila nerve cord development. Curr Opin Neurobiol 13: 8-15 PubMed GONUTS page
- ↑ 5.0 5.1 Calleja M et al. (2002) How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila. Gene 292: 1-12 PubMed GONUTS page
- ↑ 6.0 6.1 McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
- ↑ Pueyo JI et al. (2000) Proximal-distal leg development in Drosophila requires the apterous gene and the Lim1 homologue dlim1. Development 127: 5391-402 PubMed GONUTS page
- ↑ Ghazi A et al. (2000) Apterous mediates development of direct flight muscles autonomously and indirect flight muscles through epidermal cues. Development 127: 5309-18 PubMed GONUTS page
- ↑ Dworak HA & Sink H (2002) Myoblast fusion in Drosophila. Bioessays 24: 591-601 PubMed GONUTS page
- ↑ Müller D et al. (2010) Regulation and functions of the lms homeobox gene during development of embryonic lateral transverse muscles and direct flight muscles in Drosophila. PLoS One 5: e14323 PubMed GONUTS page
- ↑ Richard DS et al. (1993) A reappraisal of the hormonal regulation of larval fat body histolysis in female Drosophila melanogaster. Experientia 49: 150-6 PubMed GONUTS page
- ↑ 12.0 12.1 Pueyo JI & Couso JP (2004) Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development. Development 131: 3107-20 PubMed GONUTS page
- ↑ Furlong EE et al. (2001) Patterns of gene expression during Drosophila mesoderm development. Science 293: 1629-33 PubMed GONUTS page
- ↑ Koelzer S & Klein T (2006) Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless. Dev Biol 289: 77-90 PubMed GONUTS page
- ↑ Bejarano F et al. (2008) A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing. Genetics 178: 307-23 PubMed GONUTS page