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FB:aop

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) aop ( synonyms: AOP, Anterior open, Aop, Aop/Yan, CG3166, DROYANET, DROYANETSB, SGP cluster fusion defects 6, SK2-1, YAN, Yan, aop/yan, fus6, pok, pokkuri, yan, yan/pok )
Protein Name(s) anterior open,
External Links
FB FBgn0000097

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0147141
PMID:12175485[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000165

MAPK cascade

FB:FBrf0129916
PMID:10929403[2]

TAS: Traceable Author Statement

P

From FB

GO:0001709

cell fate determination

FB:FBrf0146938
PMID:11937027[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001751

compound eye photoreceptor cell differentiation

FB:FBrf0189914
PMID:16377567[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:95455

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0110443
PMID:10449347[5]

NAS: Non-traceable Author Statement

F

From FB

GO:0003705

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

FB:FBrf0147141
PMID:12175485[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0005515

protein binding

FB:FBrf0135901
PMID:11357138[6]

IPI: Inferred from Physical Interaction

FB:FBgn0023214

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:95455

C

From FB

GO:0005634

nucleus

FB:FBrf0147141
PMID:12175485[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0156691

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0190564
PMID:16027171[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0147141
PMID:12175485[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006897

endocytosis

FB:FBrf0187480
PMID:16014514[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0105264
PMID:9814703[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007254

JNK cascade

FB:FBrf0110443
PMID:10449347[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0187480
PMID:16014514[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0201428
PMID:17483425[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0110443
PMID:10449347[5]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0149002
PMID:12000787[11]

NAS: Non-traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[12]

TAS: Traceable Author Statement

P

From FB

GO:0007464

R3/R4 cell fate commitment

FB:FBrf0204109
PMID:18291359[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007517

muscle organ development

FB:FBrf0190556
PMID:16547170[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008406

gonad development

FB:FBrf0213539
PMID:21377458[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009987

cellular process

FB:FBrf0175143
PMID:14764878[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000418
InterPro:IPR003118

F

From FB

GO:0045316

negative regulation of compound eye photoreceptor development

FB:FBrf0156691

NAS: Non-traceable Author Statement

P

From FB

GO:0045467

R7 cell development

FB:FBrf0129916
PMID:10929403[2]

TAS: Traceable Author Statement

P

From FB

GO:0045596

negative regulation of cell differentiation

FB:FBrf0151280
PMID:12147138[12]

NAS: Non-traceable Author Statement

P

From FB

GO:0045610

regulation of hemocyte differentiation

FB:FBrf0180639
PMID:15381778[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045678

positive regulation of R7 cell differentiation

FB:FBrf0190087
PMID:16600208[18]

IGI: Inferred from Genetic Interaction

FB:FBgn0086361

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0167264
PMID:14570584[19]

TAS: Traceable Author Statement

P

From FB

GO:0046533

negative regulation of photoreceptor cell differentiation

FB:FBrf0129916
PMID:10929403[2]

TAS: Traceable Author Statement

P

From FB

GO:0046580

negative regulation of Ras protein signal transduction

FB:FBrf0079934
PMID:7888014[20]

NAS: Non-traceable Author Statement

P

From FB

GO:0048666

neuron development

FB:FBrf0190556
PMID:16547170[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048747

muscle fiber development

FB:FBrf0191368
PMID:16207075[21]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0189914
PMID:16377567[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0060233

oenocyte delamination

FB:FBrf0180129
PMID:15572130[22]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Ohshiro T et al. (2002) Ligand-dependent activation of breathless FGF receptor gene in Drosophila developing trachea. Mech Dev 114: 3-11 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
  3. Rohrbaugh M et al. (2002) Notch activation of yan expression is antagonized by RTK/pointed signaling in the Drosophila eye. Curr Biol 12: 576-81 PubMed GONUTS page
  4. 4.0 4.1 Li X & Carthew RW (2005) A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell 123: 1267-77 PubMed GONUTS page
  5. 5.0 5.1 5.2 Noselli S & Agnès F (1999) Roles of the JNK signaling pathway in Drosophila morphogenesis. Curr Opin Genet Dev 9: 466-72 PubMed GONUTS page
  6. Baker DA et al. (2001) Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila. Nature 411: 330-4 PubMed GONUTS page
  7. Song H et al. (2005) Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response. Genes Dev 19: 1767-72 PubMed GONUTS page
  8. 8.0 8.1 Schober M et al. (2005) Function of the ETS transcription factor Yan in border cell migration. Development 132: 3493-504 PubMed GONUTS page
  9. Kurada P & White K (1998) Ras promotes cell survival in Drosophila by downregulating hid expression. Cell 95: 319-29 PubMed GONUTS page
  10. Mathieu J et al. (2007) A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila. Genetics 176: 1579-90 PubMed GONUTS page
  11. Van Aelst L & Symons M (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes Dev 16: 1032-54 PubMed GONUTS page
  12. 12.0 12.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  13. Weber U et al. (2008) Combinatorial signaling by the Frizzled/PCP and Egfr pathways during planar cell polarity establishment in the Drosophila eye. Dev Biol 316: 110-23 PubMed GONUTS page
  14. 14.0 14.1 14.2 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
  15. Weyers JJ et al. (2011) A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Dev Biol 353: 217-28 PubMed GONUTS page
  16. Boutros M et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-5 PubMed GONUTS page
  17. Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page
  18. Baril C & Therrien M (2006) Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. Dev Biol 294: 232-45 PubMed GONUTS page
  19. Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  20. Chang HC et al. (1995) phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila. Cell 80: 463-72 PubMed GONUTS page
  21. Dutta D et al. (2005) Drosophila Heartless acts with Heartbroken/Dof in muscle founder differentiation. PLoS Biol 3: e337 PubMed GONUTS page
  22. Brodu V et al. (2004) EGF receptor signaling regulates pulses of cell delamination from the Drosophila ectoderm. Dev Cell 7: 885-95 PubMed GONUTS page
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