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FB:alpha-Spec
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | alpha-Spec ( synonyms: &agr-spectrin, 3A9, Alpha Spectrin, Alpha-spectrin, CG1977, Spec, Spectrin, aSpc 3A9, alfa-Spec, alpha, alpha spectrin, alpha-SPECTRIN, alpha-Sp, alpha-Spc, alpha-Spe, alpha-Spect, alpha-Spectrin, alpha-spec, alpha-spectrin, alpha-spectrin II, alphaSp, alphaSpec, alphaSpectrin, anon-EST:fe2E2, anon-fast-evolving-2E2, dre3, klo, klotzchen, l(3)04276, l(3)62Bd, l(3)alpha-Spec, l(3)dre3, spectrin ) | |
| Protein Name(s) | alpha Spectrin, | |
| External Links | ||
| FB | FBgn0250789 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002168 |
instar larval development |
FB:FBrf0078876 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0002168 |
instar larval development |
FB:FBrf0123574 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0123574 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0148886 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0152121 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005509 |
calcium ion binding |
FB:FBrf0148886 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005516 |
calmodulin binding |
FB:FBrf0123574 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005794 |
Golgi apparatus |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005811 |
lipid particle |
FB:FBrf0200342 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005856 |
cytoskeleton |
FB:FBrf0148886 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0099051 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0209342 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0210975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005938 |
cell cortex |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007009 |
plasma membrane organization |
FB:FBrf0131399 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007010 |
cytoskeleton organization |
FB:FBrf0148886 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007026 |
negative regulation of microtubule depolymerization |
FB:FBrf0187325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007274 |
neuromuscular synaptic transmission |
FB:FBrf0136992 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0091300 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007308 |
oocyte construction |
FB:FBrf0078876 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007308 |
oocyte construction |
FB:FBrf0091300 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007417 |
central nervous system development |
FB:FBrf0108204 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008017 |
microtubule binding |
FB:FBrf0131399 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0008091 |
spectrin |
FB:FBrf0123574 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0008091 |
spectrin |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0008092 |
cytoskeletal protein binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0123574 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016199 |
axon midline choice point recognition |
FB:FBrf0191925 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0250788 |
P |
From FB |
||
| GO:0016323 |
basolateral plasma membrane |
FB:FBrf0209342 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016337 |
cell-cell adhesion |
FB:FBrf0123574 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030707 |
ovarian follicle cell development |
FB:FBrf0128450 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030721 |
spectrosome organization |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030727 |
germarium-derived female germ-line cyst formation |
FB:FBrf0091300 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031594 |
neuromuscular junction |
FB:FBrf0201824 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0042062 |
long-term strengthening of neuromuscular junction |
FB:FBrf0187325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045169 |
fusome |
FB:FBrf0091300 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045170 |
spectrosome |
FB:FBrf0091300 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045170 |
spectrosome |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0045478 |
fusome organization |
FB:FBrf0108992 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045478 |
fusome organization |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048134 |
germ-line cyst formation |
FB:FBrf0108992 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048790 |
maintenance of presynaptic active zone structure |
FB:FBrf0192906 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0050807 |
regulation of synapse organization |
FB:FBrf0187325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
NOT |
GO:0008302 |
female germline ring canal formation, actin assembly |
FB:FBrf0091300 |
TAS: Traceable Author Statement |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Sisson JC et al. (2000) Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization. J Cell Biol 151: 905-18 PubMed GONUTS page
- ↑ Röper K et al. (2002) The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. J Cell Sci 115: 4215-25 PubMed GONUTS page
- ↑ Dubreuil RR et al. (1997) Segregation of two spectrin isoforms: polarized membrane-binding sites direct polarized membrane skeleton assembly. Mol Biol Cell 8: 1933-42 PubMed GONUTS page
- ↑ 4.0 4.1 Chen TW et al. (2009) Membrane domain modulation by Spectrins in Drosophila photoreceptor morphogenesis. Genesis 47: 744-50 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Pielage J et al. (2005) Presynaptic spectrin is essential for synapse stabilization. Curr Biol 15: 918-28 PubMed GONUTS page
- ↑ Featherstone DE et al. (2001) Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release. J Neurosci 21: 4215-24 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 de Cuevas M et al. (1996) alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary. Development 122: 3959-68 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ Hummel T et al. (1999) Commissure formation in the embryonic CNS of Drosophila. Dev Biol 209: 381-98 PubMed GONUTS page
- ↑ 10.0 10.1 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ Garbe DS et al. (2007) beta-Spectrin functions independently of Ankyrin to regulate the establishment and maintenance of axon connections in the Drosophila embryonic CNS. Development 134: 273-84 PubMed GONUTS page
- ↑ Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
- ↑ Kohsaka H et al. (2007) In vivo induction of postsynaptic molecular assembly by the cell adhesion molecule Fasciclin2. J Cell Biol 179: 1289-300 PubMed GONUTS page
- ↑ 14.0 14.1 Pepling ME et al. (1999) Germline cysts: a conserved phase of germ cell development? Trends Cell Biol 9: 257-62 PubMed GONUTS page
- ↑ Pielage J et al. (2006) A postsynaptic spectrin scaffold defines active zone size, spacing, and efficacy at the Drosophila neuromuscular junction. J Cell Biol 175: 491-503 PubMed GONUTS page
