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FB:alien

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) alien ( synonyms: Alien, BcDNA:LD10463, CG9556, CH2, COP9 complex homolog subunit 2, CSN2, Csn2, DCH2, Dch2, Drosophila COP9 signalosome homolog 2, d-Alien )
Protein Name(s) alien,
External Links
FB FBgn0013746

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003714

transcription corepressor activity

FB:FBrf0108335
PMID:10207062[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0004871

signal transducer activity

FB:FBrf0166152

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q15647

F

From FB

GO:0005515

protein binding

FB:FBrf0111869
PMID:10531038[2]

IPI: Inferred from Physical Interaction

FB:FBgn0027053

F

From FB

GO:0005515

protein binding

FB:FBrf0111869
PMID:10531038[2]

IPI: Inferred from Physical Interaction

FB:FBgn0028836

F

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0261530

P

From FB

GO:0007165

signal transduction

FB:FBrf0166152

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q15647

P

From FB

GO:0008180

signalosome

FB:FBrf0111869
PMID:10531038[2]

IPI: Inferred from Physical Interaction

FB:FBgn0027053

C

From FB

GO:0008180

signalosome

FB:FBrf0111869
PMID:10531038[2]

IPI: Inferred from Physical Interaction

FB:FBgn0028836

C

From FB

GO:0008180

signalosome

FB:FBrf0115042

NAS: Non-traceable Author Statement

C

From FB

GO:0008180

signalosome

FB:FBrf0174341

NAS: Non-traceable Author Statement

C

From FB

GO:0008231

repressor ecdysone receptor complex

FB:FBrf0108335
PMID:10207062[1]

IPI: Inferred from Physical Interaction

FB:FBgn0000546

C

From FB

GO:0016922

ligand-dependent nuclear receptor binding

FB:FBrf0108335
PMID:10207062[1]

IPI: Inferred from Physical Interaction

FB:FBgn0000546

F

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035257

nuclear hormone receptor binding

FB:FBrf0108335
PMID:10207062[1]

IPI: Inferred from Physical Interaction

FB:FBgn0000546

F

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0111869
PMID:10531038[2]

IPI: Inferred from Physical Interaction

FB:FBgn0013746

F

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0108335
PMID:10207062[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0050821

protein stabilization

FB:FBrf0193071
PMID:17251548[5]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Dressel U et al. (1999) Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily. Mol Cell Biol 19: 3383-94 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Freilich S et al. (1999) The COP9 signalosome is essential for development of Drosophila melanogaster. Curr Biol 9: 1187-90 PubMed GONUTS page
  3. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
  4. Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
  5. Ullah Z et al. (2007) Retinoblastoma protein regulation by the COP9 signalosome. Mol Biol Cell 18: 1179-86 PubMed GONUTS page
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