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FB:ac

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ac ( synonyms: 990 E5 F1, AC, AS-C T5, AS-C T5ac, ASC, Ac, Ac/Sc, Achaete, Achaete/Scute, Acheate, CG3796, EG:125H10.3, Hairy wing, Hairy-wing, Hw, T5, achaete-scute, achete, asc, ascT5, sc/T5 )
Protein Name(s) achaete,
External Links
FB FBgn0000022

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002805

regulation of antimicrobial peptide biosynthetic process

FB:FBrf0210846
PMID:20421637[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0055582
PMID:1525829[2]

TAS: Traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0053886
PMID:1915272[3]

ISS: Inferred from Sequence or Structural Similarity

FB:FBgn0002561

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0123499

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

NAS: Non-traceable Author Statement

C

From FB

GO:0005667

transcription factor complex

FB:FBrf0053886
PMID:1915272[3]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0053886
PMID:1915272[3]

ISS: Inferred from Sequence or Structural Similarity

FB:FBgn0002561

P

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0151319
PMID:12119094[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0007346

regulation of mitotic cell cycle

FB:FBrf0167269
PMID:14616073[5]

TAS: Traceable Author Statement

P

From FB

GO:0007399

nervous system development

FB:FBrf0055582
PMID:1525829[2]

TAS: Traceable Author Statement

P

From FB

GO:0007399

nervous system development

FB:FBrf0161619

TAS: Traceable Author Statement

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0158840
PMID:12593977[6]

TAS: Traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0123499

NAS: Non-traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0151529
PMID:12142008[7]

TAS: Traceable Author Statement

P

From FB

GO:0007419

ventral cord development

FB:FBrf0158840
PMID:12593977[6]

NAS: Non-traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0123499

NAS: Non-traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0151529
PMID:12142008[7]

TAS: Traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0190143
PMID:16084506[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0135681
PMID:11300999[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0151319
PMID:12119094[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0190143
PMID:16084506[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0075104
PMID:7821225[10]

IDA: Inferred from Direct Assay

F

From FB

GO:0045893

positive regulation of transcription, DNA-dependent

FB:FBrf0123097
PMID:10603347[11]

TAS: Traceable Author Statement

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0053776
PMID:1764999[12]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0053886
PMID:1915272[3]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0075104
PMID:7821225[10]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0048477

oogenesis

FB:FBrf0044470
PMID:3089870[13]

TAS: Traceable Author Statement

P

From FB

GO:0061331

epithelial cell proliferation involved in Malpighian tubule morphogenesis

FB:FBrf0144843
PMID:11861476[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0061382

Malpighian tubule tip cell differentiation

FB:FBrf0075100
PMID:7821213[15]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0043565

sequence-specific DNA binding

FB:FBrf0053776
PMID:1764999[12]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0043565

sequence-specific DNA binding

FB:FBrf0053886
PMID:1915272[3]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Valanne S et al. (2010) Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling. J Immunol 184: 6188-98 PubMed GONUTS page
  2. 2.0 2.1 Younger-Shepherd S et al. (1992) deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination. Cell 70: 911-22 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Cabrera CV & Alonso MC (1991) Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila. EMBO J 10: 2965-73 PubMed GONUTS page
  4. 4.0 4.1 Calleja M et al. (2002) How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila. Gene 292: 1-12 PubMed GONUTS page
  5. Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
  6. 6.0 6.1 Skeath JB & Thor S (2003) Genetic control of Drosophila nerve cord development. Curr Opin Neurobiol 13: 8-15 PubMed GONUTS page
  7. 7.0 7.1 Skaer N et al. (2002) Gene duplication at the achaete-scute complex and morphological complexity of the peripheral nervous system in Diptera. Trends Genet 18: 399-405 PubMed GONUTS page
  8. 8.0 8.1 Marcellini S et al. (2005) achaete, but not scute, is dispensable for the peripheral nervous system of Drosophila. Dev Biol 285: 545-53 PubMed GONUTS page
  9. Baker BS et al. (2001) Are complex behaviors specified by dedicated regulatory genes? Reasoning from Drosophila. Cell 105: 13-24 PubMed GONUTS page
  10. 10.0 10.1 Cabrera CV et al. (1994) Regulation of scute function by extramacrochaete in vitro and in vivo. Development 120: 3595-603 PubMed GONUTS page
  11. Lai EC et al. (2000) Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes. Development 127: 291-306 PubMed GONUTS page
  12. 12.0 12.1 Van Doren M et al. (1991) The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes. Development 113: 245-55 PubMed GONUTS page
  13. Perrimon N et al. (1986) X-linked female-sterile loci in Drosophila melanogaster. Genetics 113: 695-712 PubMed GONUTS page
  14. Sudarsan V et al. (2002) A genetic hierarchy establishes mitogenic signalling and mitotic competence in the renal tubules of Drosophila. Development 129: 935-44 PubMed GONUTS page
  15. Hoch M et al. (1994) Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development 120: 3439-50 PubMed GONUTS page
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