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FB:WASp
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | WASp ( synonyms: CG1520, D-WASP, Dm WASP, DmWASP, WASP, WSP, Wasp, Wiscott-Aldrich syndrome protein, Wiskott-Aldrich syndrome protein, Wsp, dWASP, wasp, wsp ) | |
| Protein Name(s) | WASp, | |
| External Links | ||
| FB | FBgn0024273 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001578 |
microtubule bundle formation |
FB:FBrf0208460 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0003383 |
apical constriction |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005083 |
small GTPase regulator activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0162072 |
IPI: Inferred from Physical Interaction |
FB:FBgn0020510 |
F |
From FB |
||
| GO:0005902 |
microvillus |
FB:FBrf0167774 |
IMP: Inferred from Mutant Phenotype |
C |
From FB |
|||
| GO:0007409 |
axonogenesis |
FB:FBrf0144948 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0041781 |
P |
From FB |
||
| GO:0007413 |
axonal fasciculation |
FB:FBrf0144948 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0041781 |
P |
From FB |
||
| GO:0007423 |
sensory organ development |
FB:FBrf0144805 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007520 |
myoblast fusion |
FB:FBrf0194614 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007520 |
myoblast fusion |
FB:FBrf0201865 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007520 |
myoblast fusion |
FB:FBrf0204821 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0262716 |
P |
From FB |
||
| GO:0008356 |
asymmetric cell division |
FB:FBrf0179496 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008407 |
chaeta morphogenesis |
FB:FBrf0144948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008582 |
regulation of synaptic growth at neuromuscular junction |
FB:FBrf0211075 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0009913 |
epidermal cell differentiation |
FB:FBrf0191902 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0015629 |
actin cytoskeleton |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0016028 |
rhabdomere |
FB:FBrf0167774 |
IMP: Inferred from Mutant Phenotype |
C |
From FB |
|||
| GO:0016203 |
muscle attachment |
FB:FBrf0194614 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016476 |
regulation of embryonic cell shape |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030833 |
regulation of actin filament polymerization |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0034314 |
Arp2/3 complex-mediated actin nucleation |
FB:FBrf0208460 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0035017 |
cuticle pattern formation |
FB:FBrf0191902 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035212 |
cell competition in a multicellular organism |
FB:FBrf0201270 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045165 |
cell fate commitment |
FB:FBrf0179496 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045886 |
negative regulation of synaptic growth at neuromuscular junction |
FB:FBrf0175021 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Liu R et al. (2009) Wash functions downstream of Rho and links linear and branched actin nucleation factors. Development 136: 2849-60 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Bertet C et al. (2009) Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells. Development 136: 4199-212 PubMed GONUTS page
- ↑ Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ Bogdan S & Klämbt C (2003) Kette regulates actin dynamics and genetically interacts with Wave and Wasp. Development 130: 4427-37 PubMed GONUTS page
- ↑ 5.0 5.1 Zelhof AC & Hardy RW (2004) WASp is required for the correct temporal morphogenesis of rhabdomere microvilli. J Cell Biol 164: 417-26 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Zallen JA et al. (2002) SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila. J Cell Biol 156: 689-701 PubMed GONUTS page
- ↑ Tal T et al. (2002) Conserved interactions with cytoskeletal but not signaling elements are an essential aspect of Drosophila WASp function. Dev Biol 243: 260-71 PubMed GONUTS page
- ↑ 8.0 8.1 Schäfer G et al. (2007) The Wiskott-Aldrich syndrome protein (WASP) is essential for myoblast fusion in Drosophila. Dev Biol 304: 664-74 PubMed GONUTS page
- ↑ Massarwa R et al. (2007) WIP/WASp-based actin-polymerization machinery is essential for myoblast fusion in Drosophila. Dev Cell 12: 557-69 PubMed GONUTS page
- ↑ Berger S et al. (2008) WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion. J Cell Sci 121: 1303-13 PubMed GONUTS page
- ↑ 11.0 11.1 Vartiainen MK & Machesky LM (2004) The WASP-Arp2/3 pathway: genetic insights. Curr Opin Cell Biol 16: 174-81 PubMed GONUTS page
- ↑ Nahm M et al. (2010) dCIP4 (Drosophila Cdc42-interacting protein 4) restrains synaptic growth by inhibiting the secretion of the retrograde Glass bottom boat signal. J Neurosci 30: 8138-50 PubMed GONUTS page
- ↑ 13.0 13.1 Chanut-Delalande H et al. (2006) Shavenbaby couples patterning to epidermal cell shape control. PLoS Biol 4: e290 PubMed GONUTS page
- ↑ Li W & Baker NE (2007) Engulfment is required for cell competition. Cell 129: 1215-25 PubMed GONUTS page
- ↑ Coyle IP et al. (2004) Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila. Neuron 41: 521-34 PubMed GONUTS page
