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FB:Vmat

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Vmat ( synonyms: CG33528, CG6119, CG6139, DVMAT, DVMAT-A, Drosophila vesicular monoamine transporter, VMAT, dVMAT, l(2)SH0459, l(2)SH2 0459, lethal (2) SH0459, vesicle transporter, vesicular monoamine transporter )
Protein Name(s) Vesicular monoamine transporter,
External Links
FB FBgn0260964

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005430

synaptic vesicle amine transmembrane transporter activity

FB:FBrf0187873
PMID:15849736[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0006836

neurotransmitter transport

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q01827

P

From FB

GO:0008021

synaptic vesicle

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q01827

C

From FB

GO:0008021

synaptic vesicle

FB:FBrf0210098
PMID:20053989[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0008504

monoamine transmembrane transporter activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q01827

F

From FB

GO:0008504

monoamine transmembrane transporter activity

FB:FBrf0187873
PMID:15849736[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0015238

drug transmembrane transporter activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR004734

F

From FB

GO:0015842

synaptic vesicle amine transport

FB:FBrf0187873
PMID:15849736[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0015844

monoamine transport

FB:FBrf0187873
PMID:15849736[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0015872

dopamine transport

FB:FBrf0192778
PMID:17267552[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015893

drug transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR004734

P

From FB

GO:0016021

integral to membrane

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q01827

C

From FB

GO:0031594

neuromuscular junction

FB:FBrf0187873
PMID:15849736[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0051608

histamine transport

FB:FBrf0206204
PMID:18989452[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0055085

transmembrane transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011701

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Greer CL et al. (2005) A splice variant of the Drosophila vesicular monoamine transporter contains a conserved trafficking domain and functions in the storage of dopamine, serotonin, and octopamine. J Neurobiol 64: 239-58 PubMed GONUTS page
  2. Grygoruk A et al. (2010) A tyrosine-based motif localizes a Drosophila vesicular transporter to synaptic vesicles in vivo. J Biol Chem 285: 6867-78 PubMed GONUTS page
  3. Sang TK et al. (2007) A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci 27: 981-92 PubMed GONUTS page
  4. Romero-Calderón R et al. (2008) A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. PLoS Genet 4: e1000245 PubMed GONUTS page
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