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FB:Vhl
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Vhl ( synonyms: BcDNA:RH61560, CG13221, DVhl, Dvhl, VHL, Von Hippel Lindau, d-VHL, d-vhl, dVHL, dmVHL, vhl, von Hippel Lindau ) | |
| Protein Name(s) | von Hippel-Lindau, | |
| External Links | ||
| FB | FBgn0041174 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
FB:FBrf0206144 |
IPI: Inferred from Physical Interaction |
F |
From FB |
|||
| GO:0007010 |
cytoskeleton organization |
FB:FBrf0145738 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007026 |
negative regulation of microtubule depolymerization |
FB:FBrf0210606 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0128368 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007427 |
epithelial cell migration, open tracheal system |
FB:FBrf0211250 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016334 |
establishment or maintenance of polarity of follicular epithelium |
FB:FBrf0210606 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016567 |
protein ubiquitination |
FB:FBrf0129709 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0030891 |
VCB complex |
FB:FBrf0129709 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035149 |
lumen formation, open tracheal system |
FB:FBrf0211250 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
contributes_to |
GO:0004842 |
ubiquitin-protein ligase activity |
FB:FBrf0129709 |
IDA: Inferred from Direct Assay |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gemmill RM et al. (2002) The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway. Oncogene 21: 3507-16 PubMed GONUTS page
- ↑ 2.0 2.1 Duchi S et al. (2010) Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stability. Development 137: 1493-503 PubMed GONUTS page
- ↑ Adryan B et al. (2000) Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila. Oncogene 19: 2803-11 PubMed GONUTS page
- ↑ 4.0 4.1 Hsouna A et al. (2010) Drosophila von Hippel-Lindau tumor suppressor gene function in epithelial tubule morphogenesis. Mol Cell Biol 30: 3779-94 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Aso T et al. (2000) Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity. Biochem Biophys Res Commun 276: 355-61 PubMed GONUTS page
