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FB:Utx

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Utx ( synonyms: CG5640, anon-31BCa, dUTX, dUtx )
Protein Name(s) No Information Provided.
External Links
FB FBgn0260749

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005488

binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011990

F

From FB

GO:0005634

nucleus

FB:FBrf0203005
PMID:18039863[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005705

polytene chromosome interband

FB:FBrf0203005
PMID:18039863[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0008285

negative regulation of cell proliferation

FB:FBrf0210661
PMID:20212086[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016577

histone demethylation

FB:FBrf0203005
PMID:18039863[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0032452

histone demethylase activity

FB:FBrf0203005
PMID:18039863[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:12637

F

From FB

GO:0045498

sex comb development

FB:FBrf0210661
PMID:20212086[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045746

negative regulation of Notch signaling pathway

FB:FBrf0210661
PMID:20212086[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0000463

P

From FB

GO:0045746

negative regulation of Notch signaling pathway

FB:FBrf0210661
PMID:20212086[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0004197

P

From FB

GO:0045746

negative regulation of Notch signaling pathway

FB:FBrf0210661
PMID:20212086[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0004647

P

From FB

GO:0051568

histone H3-K4 methylation

FB:FBrf0210661
PMID:20212086[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0071557

histone H3-K27 demethylation

FB:FBrf0210661
PMID:20212086[2]

IMP: Inferred from Mutant Phenotype

P

From FB

colocalizes_with

GO:0035327

transcriptionally active chromatin

FB:FBrf0203005
PMID:18039863[1]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Smith ER et al. (2008) Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol 28: 1041-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Herz HM et al. (2010) The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila. Mol Cell Biol 30: 2485-97 PubMed GONUTS page
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