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FB:Trf2

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Trf2 ( synonyms: CG11195, CG18009, TATA box-binding protein related factor 2, TBP related factor 2, TBP-like factor, TBP-related factor 2, TLF, TRF2, dTRF2, dTrf2, l(1)G0039, l(1)G0071, l(1)G0295, l(1)G0425, lethal (1) G0039, lethal (1) G0071, lethal (1) G0295, lethal (1) G0425, p79/TRF2, trf2 )
Protein Name(s) TATA box binding protein-related factor 2,
External Links
FB FBgn0261793

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001673

male germ cell nucleus

FB:FBrf0192356
PMID:17015475[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0001674

female germ cell nucleus

FB:FBrf0192356
PMID:17015475[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0003677

DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000814
InterPro:IPR012294

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0155489
PMID:12459787[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0162294
PMID:12878007[3]

TAS: Traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0155489
PMID:12459787[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0192356
PMID:17015475[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005667

transcription factor complex

FB:FBrf0155489
PMID:12459787[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11588

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11589

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0000950

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

WP:CE01408

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

WP:CE16453

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0192356
PMID:17015475[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0155489
PMID:12459787[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0155489
PMID:12459787[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006366

transcription from RNA polymerase II promoter

FB:FBrf0155489
PMID:12459787[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11588

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11589

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0000950

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

WP:CE01408

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[4]

ISS: Inferred from Sequence or Structural Similarity

WP:CE16453

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0162294
PMID:12878007[3]

TAS: Traceable Author Statement

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035071

salivary gland cell autophagic cell death

FB:FBrf0201083
PMID:17948312[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035075

response to ecdysone

FB:FBrf0201083
PMID:17948312[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035209

pupal development

FB:FBrf0201083
PMID:17948312[5]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0155489
PMID:12459787[2]

IPI: Inferred from Physical Interaction

FB:FBgn0015664

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Kopytova DV et al. (2006) Two isoforms of Drosophila TRF2 are involved in embryonic development, premeiotic chromatin condensation, and proper differentiation of germ cells of both sexes. Mol Cell Biol 26: 7492-505 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Hochheimer A et al. (2002) TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila. Nature 420: 439-45 PubMed GONUTS page
  3. 3.0 3.1 Davidson I (2003) The genetics of TBP and TBP-related factors. Trends Biochem Sci 28: 391-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 Aoyagi N & Wassarman DA (2000) Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation. J Cell Biol 150: F45-50 PubMed GONUTS page
  5. 5.0 5.1 5.2 Bashirullah A et al. (2007) dTrf2 is required for transcriptional and developmental responses to ecdysone during Drosophila metamorphosis. Dev Dyn 236: 3173-9 PubMed GONUTS page
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