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FB:Tor
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Tor ( synonyms: 5092, CG5092, CT16317, CT24745, CT24817, DmTOR, FRAP/TOR, TOR, Target Of Rapamycin, Target of Rapamycin, Target-of-rapamycin, dTOR, dTor, dtor, l(2)k17004, mTOR, mTor, target of rapamycin, target of rapamycin kinase, target-of-rapamycin, tor ) | |
| Protein Name(s) | Target of rapamycin, | |
| External Links | ||
| FB | FBgn0021796 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001558 |
regulation of cell growth |
FB:FBrf0195068 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
FB:FBrf0209636 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0005198 |
P |
From FB |
||
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0006914 |
autophagy |
FB:FBrf0180117 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006974 |
response to DNA damage stimulus |
FB:FBrf0208272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007584 |
response to nutrient |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007584 |
response to nutrient |
FB:FBrf0159230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0179269 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008406 |
gonad development |
FB:FBrf0190780 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009594 |
detection of nutrient |
FB:FBrf0136845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016310 |
phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0141377 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0156084 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0162295 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0032456 |
endocytic recycling |
FB:FBrf0195068 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0035264 |
multicellular organism growth |
FB:FBrf0190780 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040007 |
growth |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0159230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0043621 |
protein self-association |
FB:FBrf0190780 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0136845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0159230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0202261 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0209636 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0005198 |
P |
From FB |
||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0209636 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0136845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0209531 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0090070 |
positive regulation of ribosome biogenesis |
FB:FBrf0202261 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:2000377 |
regulation of reactive oxygen species metabolic process |
FB:FBrf0210161 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0013984 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hennig KM et al. (2006) TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. J Cell Biol 173: 963-74 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Cully M et al. (2010) A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. Mol Cell Biol 30: 481-95 PubMed GONUTS page
- ↑ 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Scott RC et al. (2004) Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev Cell 7: 167-78 PubMed GONUTS page
- ↑ Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
- ↑ 6.0 6.1 Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Jacinto E & Hall MN (2003) Tor signalling in bugs, brain and brawn. Nat Rev Mol Cell Biol 4: 117-26 PubMed GONUTS page
- ↑ Kapahi P et al. (2004) Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr Biol 14: 885-90 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Zhang Y et al. (2006) Drosophila target of rapamycin kinase functions as a multimer. Genetics 172: 355-62 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ Johnston LA & Gallant P (2002) Control of growth and organ size in Drosophila. Bioessays 24: 54-64 PubMed GONUTS page
- ↑ Oldham S & Hafen E (2003) Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 13: 79-85 PubMed GONUTS page
- ↑ Bergmann A & Lane ME (2003) HIDden targets of microRNAs for growth control. Trends Biochem Sci 28: 461-3 PubMed GONUTS page
- ↑ 14.0 14.1 Hall DJ et al. (2007) Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila. BMC Biol 5: 10 PubMed GONUTS page
- ↑ Koike-Kumagai M et al. (2009) The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway. EMBO J 28: 3879-92 PubMed GONUTS page
- ↑ Lee JH et al. (2010) Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science 327: 1223-8 PubMed GONUTS page
