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FB:Topors

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Topors ( synonyms: CG15104, TOPORS, dTopors, dtopors )
Protein Name(s) Topoisomerase I-interacting protein,
External Links
FB FBgn0034410

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0174781
PMID:14871887[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0005634

nucleus

FB:FBrf0191177
PMID:16209949[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005652

nuclear lamina

FB:FBrf0191177
PMID:16209949[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0191177
PMID:16209949[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0261530

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001841

F

From FB

GO:0017033

DNA topoisomerase I binding

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

protein_id:AAD23379.1

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ Secombe J & Parkhurst SM (2004) Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein. J Biol Chem 279: 17126-33 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 Capelson M & Corces VG (2005) The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator. Mol Cell 20: 105-16 PubMed GONUTS page
  3. ↑ Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the Gā‚‚-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
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