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FB:Topors
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Topors ( synonyms: CG15104, TOPORS, dTopors, dtopors ) | |
| Protein Name(s) | Topoisomerase I-interacting protein, | |
| External Links | ||
| FB | FBgn0034410 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004842 |
ubiquitin-protein ligase activity |
FB:FBrf0174781 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0191177 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005652 |
nuclear lamina |
FB:FBrf0191177 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005700 |
polytene chromosome |
FB:FBrf0191177 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261530 |
P |
From FB |
||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0017033 |
DNA topoisomerase I binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAD23379.1 |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ā Secombe J & Parkhurst SM (2004) Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein. J Biol Chem 279: 17126-33 PubMed GONUTS page
- ā 2.0 2.1 2.2 Capelson M & Corces VG (2005) The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator. Mol Cell 20: 105-16 PubMed GONUTS page
- ā Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the Gā-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page