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FB:Tbp

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Tbp ( synonyms: 42kDa polypeptide, CG9874, RBP, TATA box binding protein, TATA box-binding protein, TATA-binding protein, TATA-box binding protein, TBP, TBP38, TFIID, TFIIDtau, TfIID, dTBP, dTFIID, dTbp, dtbp )
Protein Name(s) TATA binding protein,
External Links
FB FBgn0003687

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001092

TFIIA-class transcription factor binding

FB:FBrf0064763
PMID:8224849[1]

IPI: Inferred from Physical Interaction

FB:FBgn0011289

F

From FB

GO:0001129

TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly

FB:FBrf0065619
PMID:8276241[2]

IPI: Inferred from Physical Interaction

FB:FBgn0011290

F

From FB

GO:0003677

DNA binding

FB:FBrf0123721

NAS: Non-traceable Author Statement

F

From FB

GO:0003677

DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000814
InterPro:IPR012294

F

From FB

GO:0005515

protein binding

FB:FBrf0155720
PMID:12506002[3]

IPI: Inferred from Physical Interaction

FB:FBgn0262732

F

From FB

GO:0005634

nucleus

FB:FBrf0051357
PMID:2194666[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0123721

NAS: Non-traceable Author Statement

C

From FB

GO:0005666

DNA-directed RNA polymerase III complex

FB:FBrf0090837
PMID:8943346[5]

IC: Inferred by Curator

GO:0006359
GO:0042797
GO:0042796

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0123721

NAS: Non-traceable Author Statement

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11588

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11589

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0000950

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

WP:CE01408

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

WP:CE16453

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0192616
PMID:16895980[7]

IPI: Inferred from Physical Interaction

FB:FBgn0010280

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0192616
PMID:16895980[7]

IPI: Inferred from Physical Interaction

FB:FBgn0010417

C

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0123721

NAS: Non-traceable Author Statement

P

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0162294
PMID:12878007[8]

TAS: Traceable Author Statement

P

From FB

GO:0006359

regulation of transcription from RNA polymerase III promoter

FB:FBrf0090837
PMID:8943346[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0051357
PMID:2194666[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11588

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11589

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0000950

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

WP:CE01408

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

WP:CE16453

P

From FB

GO:0008134

transcription factor binding

FB:FBrf0089397
PMID:8170939[9]

IPI: Inferred from Physical Interaction

FB:FBgn0010355

F

From FB

GO:0008134

transcription factor binding

FB:FBrf0097691
PMID:9218440[10]

IPI: Inferred from Physical Interaction

FB:FBgn0022356

F

From FB

GO:0042796

snRNA transcription from RNA polymerase III promoter

FB:FBrf0090837
PMID:8943346[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0042797

tRNA transcription from RNA polymerase III promoter

FB:FBrf0090837
PMID:8943346[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0042797

tRNA transcription from RNA polymerase III promoter

FB:FBrf0097691
PMID:9218440[10]

IDA: Inferred from Direct Assay

P

From FB

GO:0042797

tRNA transcription from RNA polymerase III promoter

FB:FBrf0097691
PMID:9218440[10]

IMP: Inferred from Mutant Phenotype

P

From FB

colocalizes_with

GO:0000126

transcription factor TFIIIB complex

FB:FBrf0097691
PMID:9218440[10]

IPI: Inferred from Physical Interaction

FB:FBgn0022356

C

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0051357
PMID:2194666[4]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11588

F

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0129705
PMID:10908585[6]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0000950

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Yokomori K et al. (1993) Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex. Genes Dev 7: 2235-45 PubMed GONUTS page
  2. Yokomori K et al. (1993) Molecular cloning and characterization of dTAFII30 alpha and dTAFII30 beta: two small subunits of Drosophila TFIID. Genes Dev 7: 2587-97 PubMed GONUTS page
  3. Liu QX et al. (2003) Drosophila MBF1 is a co-activator for Tracheae Defective and contributes to the formation of tracheal and nervous systems. Development 130: 719-28 PubMed GONUTS page
  4. 4.0 4.1 4.2 Hoey T et al. (1990) Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID. Cell 61: 1179-86 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Trivedi A et al. (1996) TATA-binding protein is limiting for both TATA-containing and TATA-lacking RNA polymerase III promoters in Drosophila cells. Mol Cell Biol 16: 6909-16 PubMed GONUTS page
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 Aoyagi N & Wassarman DA (2000) Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation. J Cell Biol 150: F45-50 PubMed GONUTS page
  7. 7.0 7.1 Wright KJ et al. (2006) TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter. Proc Natl Acad Sci U S A 103: 12347-52 PubMed GONUTS page
  8. Davidson I (2003) The genetics of TBP and TBP-related factors. Trends Biochem Sci 28: 391-8 PubMed GONUTS page
  9. Kokubo T et al. (1994) Interaction between the N-terminal domain of the 230-kDa subunit and the TATA box-binding subunit of TFIID negatively regulates TATA-box binding. Proc Natl Acad Sci U S A 91: 3520-4 PubMed GONUTS page
  10. 10.0 10.1 10.2 10.3 Vilalta A et al. (1997) An RNA polymerase III-defective mutation in TATA-binding protein disrupts its interaction with a transcription factor IIIB subunit in drosophila cells. J Biol Chem 272: 18087-92 PubMed GONUTS page
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