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FB:Tak1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Tak1 ( synonyms: CG1388, CG18492, D-TAK, D-tak, D10, DTAK1, DTak, DTak1, DmTak1, TAK, TAK-1, TAK1, TGF-beta activated-kinase 1, TGFbeta-activated kinase 1, Tak, Tak 1, dTAK, dTAK-1, dTAK1, dTak, dTak1, dtak1, tak, tak1, transforming growth factor-beta-activated kinase 1 ) | |
| Protein Name(s) | TGF-beta activated kinase 1, | |
| External Links | ||
| FB | FBgn0026323 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004706 |
JUN kinase kinase kinase activity |
FB:FBrf0167753 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0106385 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0106998 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0127351 |
ISS: Inferred from Sequence or Structural Similarity |
NCBI_NP:663305 |
F |
From FB |
||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0174342 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005575 |
cellular component |
FB:FBrf0159398 |
ND: No biological Data available |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0106998 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0127351 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003997 |
P |
From FB |
||
| GO:0006915 |
apoptotic process |
FB:FBrf0127351 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0011706 |
P |
From FB |
||
| GO:0006915 |
apoptotic process |
FB:FBrf0127351 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0015946 |
P |
From FB |
||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0167753 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0179043 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0174342 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007249 |
I-kappaB kinase/NF-kappaB cascade |
FB:FBrf0167753 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007254 |
JNK cascade |
FB:FBrf0106998 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007254 |
JNK cascade |
FB:FBrf0127351 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000229 |
P |
From FB |
||
| GO:0007254 |
JNK cascade |
FB:FBrf0127351 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010303 |
P |
From FB |
||
| GO:0007256 |
activation of JNKK activity |
FB:FBrf0167753 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0127351 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016318 |
ommatidial rotation |
FB:FBrf0135880 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045087 |
innate immune response |
FB:FBrf0161623 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0189754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0127351 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048802 |
notum morphogenesis |
FB:FBrf0135880 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050829 |
defense response to Gram-negative bacterium |
FB:FBrf0192381 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050829 |
defense response to Gram-negative bacterium |
FB:FBrf0192958 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0030695 |
P |
From FB |
||
| GO:0051607 |
defense response to virus |
FB:FBrf0209015 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0071222 |
cellular response to lipopolysaccharide |
FB:FBrf0189754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Silverman N et al. (2003) Immune activation of NF-kappaB and JNK requires Drosophila TAK1. J Biol Chem 278: 48928-34 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Takatsu Y et al. (2000) TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development. Mol Cell Biol 20: 3015-26 PubMed GONUTS page
- ↑ 4.0 4.1 Brennan CA & Anderson KV (2004) Drosophila: the genetics of innate immune recognition and response. Annu Rev Immunol 22: 457-83 PubMed GONUTS page
- ↑ Leclerc V & Reichhart JM (2004) The immune response of Drosophila melanogaster. Immunol Rev 198: 59-71 PubMed GONUTS page
- ↑ Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ 7.0 7.1 Mihaly J et al. (2001) The role of the Drosophila TAK homologue dTAK during development. Mech Dev 102: 67-79 PubMed GONUTS page
- ↑ 8.0 8.1 Ryabinina OP et al. (2006) D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells. BMC Cell Biol 7: 7 PubMed GONUTS page
- ↑ Leulier F et al. (2006) The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection. Mol Cell Biol 26: 7821-31 PubMed GONUTS page
- ↑ Libert S et al. (2006) Trade-offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFkappaB signaling. Aging Cell 5: 533-43 PubMed GONUTS page
- ↑ Costa A et al. (2009) The Imd pathway is involved in antiviral immune responses in Drosophila. PLoS One 4: e7436 PubMed GONUTS page
