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FB:Taf1

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Taf1 ( synonyms: BG:DS00004.13, CG17603, EfW1, SR3-5, Suppressor of Ras85D 3-5, TAF, TAF1, TAF200, TAF230, TAF250, TAF250/230, TAFII-250, TAFII250, TAF(II)250, TAF((II)), TAF((II))230, TAF((II))250, TAF((II))250/230, TATA-associated factor 250, TBP-associated factor, TBP-associated factor 250, TBP-associated factor 250kD, TFIID, TFIID 230 kda subunit, TFIID TAF250, Taf1p, Taf200, Taf230, Taf250, Taf((II))250, cel, cell, cell lethal, d230, dTAF230, dTAF250, dTAFII250, dTAF((II))230, dTAF((II))250, dmTAF1, dmTAF((II))230, l(3)84Ab, p230 )
Protein Name(s) TBP-associated factor 1,
External Links
FB FBgn0010355

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000117

regulation of transcription involved in G2/M-phase of mitotic cell cycle

FB:FBrf0175145
PMID:15143281[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001129

TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly

FB:FBrf0089397
PMID:8170939[2]

IPI: Inferred from Physical Interaction

FB:FBgn0003687

F

From FB

GO:0003677

DNA binding

FB:FBrf0156867

NAS: Non-traceable Author Statement

F

From FB

GO:0004672

protein kinase activity

FB:FBrf0151620

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0083171
PMID:7664336[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0156867

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0192616
PMID:16895980[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0083171
PMID:7664336[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0117006

NAS: Non-traceable Author Statement

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11535

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0129705
PMID:10908585[5]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0001039

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0192616
PMID:16895980[4]

IPI: Inferred from Physical Interaction

FB:FBgn0010280

C

From FB

GO:0005669

transcription factor TFIID complex

FB:FBrf0192616
PMID:16895980[4]

IPI: Inferred from Physical Interaction

FB:FBgn0010417

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0156867

NAS: Non-traceable Author Statement

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:11535

P

From FB

GO:0006367

transcription initiation from RNA polymerase II promoter

FB:FBrf0129705
PMID:10908585[5]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0001039

P

From FB

GO:0006461

protein complex assembly

FB:FBrf0156867

NAS: Non-traceable Author Statement

P

From FB

GO:0008134

transcription factor binding

FB:FBrf0065619
PMID:8276241[6]

IPI: Inferred from Physical Interaction

FB:FBgn0011290

F

From FB

GO:0008134

transcription factor binding

FB:FBrf0065619
PMID:8276241[6]

IPI: Inferred from Physical Interaction

FB:FBgn0011291

F

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001878

F

From FB

GO:0016573

histone acetylation

FB:FBrf0175145
PMID:15143281[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035174

histone serine kinase activity

FB:FBrf0175145
PMID:15143281[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0191934
PMID:16893881[7]

IDA: Inferred from Direct Assay

F

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0192616
PMID:16895980[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0046425

regulation of JAK-STAT cascade

FB:FBrf0212202
PMID:20624926[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051726

regulation of cell cycle

FB:FBrf0156867

NAS: Non-traceable Author Statement

P

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0083625
PMID:7600579[9]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0191934
PMID:16893881[7]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0001075

RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly

FB:FBrf0192616
PMID:16895980[4]

IDA: Inferred from Direct Assay

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Maile T et al. (2004) TAF1 activates transcription by phosphorylation of serine 33 in histone H2B. Science 304: 1010-4 PubMed GONUTS page
  2. Kokubo T et al. (1994) Interaction between the N-terminal domain of the 230-kDa subunit and the TATA box-binding subunit of TFIID negatively regulates TATA-box binding. Proc Natl Acad Sci U S A 91: 3520-4 PubMed GONUTS page
  3. 3.0 3.1 Hansen SK & Tjian R (1995) TAFs and TFIIA mediate differential utilization of the tandem Adh promoters. Cell 82: 565-75 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Wright KJ et al. (2006) TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter. Proc Natl Acad Sci U S A 103: 12347-52 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Aoyagi N & Wassarman DA (2000) Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation. J Cell Biol 150: F45-50 PubMed GONUTS page
  6. 6.0 6.1 Yokomori K et al. (1993) Molecular cloning and characterization of dTAFII30 alpha and dTAFII30 beta: two small subunits of Drosophila TFIID. Genes Dev 7: 2587-97 PubMed GONUTS page
  7. 7.0 7.1 Metcalf CE & Wassarman DA (2006) DNA binding properties of TAF1 isoforms with two AT-hooks. J Biol Chem 281: 30015-23 PubMed GONUTS page
  8. Kallio J et al. (2010) Eye transformer is a negative regulator of Drosophila JAK/STAT signaling. FASEB J 24: 4467-79 PubMed GONUTS page
  9. Verrijzer CP et al. (1995) Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell 81: 1115-25 PubMed GONUTS page
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