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FB:TBPH

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) TBPH ( synonyms: CG10327, TAR DNA binding protein, TDP-43, TDP43, dTDP, dtar, tbph )
Protein Name(s) TAR DNA-binding protein-43 homolog,
External Links
FB FBgn0025790

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012677

F

From FB

GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000504

F

From FB

GO:0003729

mRNA binding

FB:FBrf0129923
PMID:10908586[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005634

nucleus

FB:FBrf0213971
PMID:21673800[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007528

neuromuscular junction development

FB:FBrf0208082
PMID:19379745[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008344

adult locomotory behavior

FB:FBrf0208082
PMID:19379745[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008344

adult locomotory behavior

FB:FBrf0216240
PMID:21881207[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045886

negative regulation of synaptic growth at neuromuscular junction

FB:FBrf0213971
PMID:21673800[2]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
  2. 2.0 2.1 Lin MJ et al. (2011) Neuronal function and dysfunction of Drosophila dTDP. PLoS One 6: e20371 PubMed GONUTS page
  3. 3.0 3.1 Feiguin F et al. (2009) Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior. FEBS Lett 583: 1586-92 PubMed GONUTS page
  4. Wang JW et al. (2011) The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest 121: 4118-26 PubMed GONUTS page
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