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FB:Su(var)3-9
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Su(var)3-9 ( synonyms: CG6476, E(var)3-2, Enhancer of variegation 3-2, SU(VAR)3-9, SUV39, SUV39H1, Su(Var)3-9, Su(var), Su(var) 3-9, Su(var)3-902, Su(var)306, Su(var)310, Su(var)328, Su-var(3)9, Su-var(3)902, SuVar3-9, Suppressor of variegation 306, Suppressor of variegation 310, Suppressor of variegation 328, Suv 3-9, Suvar(3)9, Suvar3-9, Suvar39, caa56376 Suvar39 Dm, dSU(VAR)3-9, dSu(var)3-9, histone methyltransferase, pitkin, ptn, su(var)3-9 ) | |
| Protein Name(s) | Suppressor of variegation 3-9, | |
| External Links | ||
| FB | FBgn0263755 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000775 |
chromosome, centromeric region |
FB:FBrf0161618 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0000775 |
chromosome, centromeric region |
FB:FBrf0173280 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0000792 |
heterochromatin |
FB:FBrf0124042 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0000792 |
heterochromatin |
FB:FBrf0161618 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0000792 |
heterochromatin |
FB:FBrf0173280 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0003682 |
chromatin binding |
FB:FBrf0124042 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003924 |
GTPase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005525 |
GTP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0124042 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000953 |
C |
From FB |
||
| GO:0005701 |
polytene chromosome chromocenter |
FB:FBrf0213472 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006306 |
DNA methylation |
FB:FBrf0162085 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006325 |
chromatin organization |
FB:FBrf0155808 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006325 |
chromatin organization |
FB:FBrf0159913 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006342 |
chromatin silencing |
FB:FBrf0147067 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006348 |
chromatin silencing at telomere |
FB:FBrf0147067 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0016458 |
gene silencing |
FB:FBrf0144851 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016458 |
gene silencing |
FB:FBrf0161700 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016570 |
histone modification |
FB:FBrf0155808 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016571 |
histone methylation |
FB:FBrf0173275 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016571 |
histone methylation |
FB:FBrf0174387 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0030702 |
chromatin silencing at centromere |
FB:FBrf0147067 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031507 |
heterochromatin assembly |
FB:FBrf0200644 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042054 |
histone methyltransferase activity |
FB:FBrf0139647 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0042054 |
histone methyltransferase activity |
FB:FBrf0155808 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0042054 |
histone methyltransferase activity |
FB:FBrf0174387 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0042054 |
histone methyltransferase activity |
FB:FBrf0180260 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0046974 |
histone methyltransferase activity (H3-K9 specific) |
FB:FBrf0139647 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0046974 |
histone methyltransferase activity (H3-K9 specific) |
FB:FBrf0161618 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0046974 |
histone methyltransferase activity (H3-K9 specific) |
FB:FBrf0161700 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0046974 |
histone methyltransferase activity (H3-K9 specific) |
FB:FBrf0173275 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0048132 |
female germ-line stem cell division |
FB:FBrf0210280 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0134644 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0210280 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0195109 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051567 |
histone H3-K9 methylation |
FB:FBrf0139647 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0051567 |
histone H3-K9 methylation |
FB:FBrf0180260 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051567 |
histone H3-K9 methylation |
FB:FBrf0208478 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0070868 |
heterochromatin organization involved in chromatin silencing |
FB:FBrf0209635 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 McNairn AJ & Gilbert DM (2003) Epigenomic replication: linking epigenetics to DNA replication. Bioessays 25: 647-56 PubMed GONUTS page
- ↑ 2.0 2.1 Zhimulev IF & Belyaeva ES (2003) Intercalary heterochromatin and genetic silencing. Bioessays 25: 1040-51 PubMed GONUTS page
- ↑ Koryakov DE et al. (2011) The SUUR protein is involved in binding of SU(VAR)3-9 and methylation of H3K9 and H3K27 in chromosomes of Drosophila melanogaster. Chromosome Res 19: 235-49 PubMed GONUTS page
- ↑ Kunert N et al. (2003) A Dnmt2-like protein mediates DNA methylation in Drosophila. Development 130: 5083-90 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Ner SS et al. (2002) A role for the Drosophila SU(VAR)3-9 protein in chromatin organization at the histone gene cluster and in suppression of position-effect variegation. Genetics 162: 1763-74 PubMed GONUTS page
- ↑ Schneider R et al. (2002) Unsafe SETs: histone lysine methyltransferases and cancer. Trends Biochem Sci 27: 396-402 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Donaldson KM et al. (2002) Modifiers of terminal deficiency-associated position effect variegation in Drosophila. Genetics 160: 995-1009 PubMed GONUTS page
- ↑ Schotta G et al. (2002) Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J 21: 1121-31 PubMed GONUTS page
- ↑ 9.0 9.1 Eskeland R et al. (2004) The N-terminus of Drosophila SU(VAR)3-9 mediates dimerization and regulates its methyltransferase activity. Biochemistry 43: 3740-9 PubMed GONUTS page
- ↑ Andreyeva EN et al. (2007) High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mutants. Proc Natl Acad Sci U S A 104: 12819-24 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Czermin B et al. (2001) Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila. EMBO Rep 2: 915-9 PubMed GONUTS page
- ↑ 12.0 12.1 Ebert A et al. (2004) Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev 18: 2973-83 PubMed GONUTS page
- ↑ 13.0 13.1 Yoon J et al. (2008) dSETDB1 and SU(VAR)3-9 sequentially function during germline-stem cell differentiation in Drosophila melanogaster. PLoS One 3: e2234 PubMed GONUTS page
- ↑ Kuhfittig S et al. (2001) pitkin(D), a novel gain-of-function enhancer of position-effect variegation, affects chromatin regulation during oogenesis and early embryogenesis in Drosophila. Genetics 157: 1227-44 PubMed GONUTS page
- ↑ Demakova OV et al. (2007) The SU(VAR)3-9/HP1 complex differentially regulates the compaction state and degree of underreplication of X chromosome pericentric heterochromatin in Drosophila melanogaster. Genetics 175: 609-20 PubMed GONUTS page
- ↑ Gracheva E et al. (2009) Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation. PLoS One 4: e6182 PubMed GONUTS page
- ↑ Fagegaltier D et al. (2009) The endogenous siRNA pathway is involved in heterochromatin formation in Drosophila. Proc Natl Acad Sci U S A 106: 21258-63 PubMed GONUTS page
