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FB:Su(var)2-10

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Su(var)2-10 ( synonyms: CG8068, CLOT2057, DPIAS, Dpias, PIAS, SU(VAR)2-10, Su(Var)2-10, Su(var)-10, Su-var(2)10, Suvar(2)10, ZIMP, ZimpA, ZimpB, dPIAS, dpias, i184, l(2)03697, pias, protein inhibitor of activated STAT, suppressor of variegation 2-10, zimp, zinc finger-containing Miz1 PIAS3-like )
Protein Name(s) Suppressor of variegation 2-10,
External Links
FB FBgn0003612

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR003034

F

From FB

GO:0003677

DNA binding

FB:FBrf0136940
PMID:11390354[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005634

nucleus

FB:FBrf0136940
PMID:11390354[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0151864
PMID:12194841[2]

TAS: Traceable Author Statement

C

From FB

GO:0005652

nuclear lamina

FB:FBrf0136940
PMID:11390354[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005654

nucleoplasm

FB:FBrf0136940
PMID:11390354[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0136940
PMID:11390354[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0136940
PMID:11390354[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0151864
PMID:12194841[2]

TAS: Traceable Author Statement

C

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0261530

P

From FB

GO:0007446

imaginal disc growth

FB:FBrf0141375
PMID:11746233[4]

TAS: Traceable Author Statement

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR004181

F

From FB

GO:0017151

DEAD/H-box RNA helicase binding

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030097

hemopoiesis

FB:FBrf0167476
PMID:14602069[5]

TAS: Traceable Author Statement

P

From FB

GO:0030261

chromosome condensation

FB:FBrf0136940
PMID:11390354[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035012

polytene chromosome, telomeric region

FB:FBrf0136940
PMID:11390354[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0042176

regulation of protein catabolic process

FB:FBrf0151864
PMID:12194841[2]

TAS: Traceable Author Statement

P

From FB

GO:0046425

regulation of JAK-STAT cascade

FB:FBrf0151864
PMID:12194841[2]

TAS: Traceable Author Statement

P

From FB

GO:0046426

negative regulation of JAK-STAT cascade

FB:FBrf0167476
PMID:14602069[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0048749

compound eye development

FB:FBrf0137351
PMID:11504941[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0141375
PMID:11746233[4]

TAS: Traceable Author Statement

P

From FB

GO:0051276

chromosome organization

FB:FBrf0136940
PMID:11390354[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051276

chromosome organization

FB:FBrf0141375
PMID:11746233[4]

TAS: Traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Hari KL et al. (2001) The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family. Genes Dev 15: 1334-48 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Hombría JC & Brown S (2002) The fertile field of Drosophila Jak/STAT signalling. Curr Biol 12: R569-75 PubMed GONUTS page
  3. Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
  4. 4.0 4.1 4.2 Luo H & Dearolf CR (2001) The JAK/STAT pathway and Drosophila development. Bioessays 23: 1138-47 PubMed GONUTS page
  5. 5.0 5.1 Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
  6. Betz A et al. (2001) A Drosophila PIAS homologue negatively regulates stat92E. Proc Natl Acad Sci U S A 98: 9563-8 PubMed GONUTS page
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