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FB:Src64B

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Src64B ( synonyms: C-src1, CG7524, D-Src64B, D-src, DSRC64, DSrc, DSrc64, DSrc64B, Dm SRC1, DmHD-358, Dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, SRC 64B, Src, Src proto oncogene sequence, Src1, Src64, c-src, dSrc, dsrc, mRNA-like ncRNA in embryogenesis 5, src, src1, src64, src64B, src64b )
Protein Name(s) Src oncogene at 64B,
External Links
FB FBgn0262733

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004713

protein tyrosine kinase activity

FB:FBrf0042057
PMID:2996778[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0118627

NAS: Non-traceable Author Statement

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0123322

NAS: Non-traceable Author Statement

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008266
InterPro:IPR020635

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0151782
PMID:12014990[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0004603

P

From FB

GO:0007254

JNK cascade

FB:FBrf0151280
PMID:12147138[4]

TAS: Traceable Author Statement

P

From FB

GO:0007293

germarium-derived egg chamber formation

FB:FBrf0194413
PMID:16775001[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007300

ovarian nurse cell to oocyte transport

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007301

female germline ring canal formation

FB:FBrf0103249
PMID:9655810[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007301

female germline ring canal formation

FB:FBrf0194413
PMID:16775001[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007349

cellularization

FB:FBrf0167540
PMID:14736750[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[4]

TAS: Traceable Author Statement

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0201960
PMID:17507403[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007611

learning or memory

FB:FBrf0159552
PMID:12593794[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008064

regulation of actin polymerization or depolymerization

FB:FBrf0144949
PMID:11854310[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008302

female germline ring canal formation, actin assembly

FB:FBrf0144949
PMID:11854310[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008335

female germline ring canal stabilization

FB:FBrf0103249
PMID:9655810[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008355

olfactory learning

FB:FBrf0159552
PMID:12593794[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016319

mushroom body development

FB:FBrf0167790
PMID:14608664[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0018108

peptidyl-tyrosine phosphorylation

FB:FBrf0151782
PMID:12014990[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0004603

P

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030046

parallel actin filament bundle assembly

FB:FBrf0144949
PMID:11854310[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030708

germarium-derived female germ-line cyst encapsulation

FB:FBrf0194413
PMID:16775001[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030717

karyosome formation

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030723

ovarian fusome organization

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045172

germline ring canal

FB:FBrf0132360
PMID:11131529[13]

TAS: Traceable Author Statement

C

From FB

GO:0045172

germline ring canal

FB:FBrf0194413
PMID:16775001[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0048477

oogenesis

FB:FBrf0187382
PMID:15979065[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Simon MA et al. (1985) The nucleotide sequence and the tissue-specific expression of Drosophila c-src. Cell 42: 831-40 PubMed GONUTS page
  2. 2.0 2.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  3. 3.0 3.1 Muda M et al. (2002) Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem J 366: 73-7 PubMed GONUTS page
  4. 4.0 4.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 O'Reilly AM et al. (2006) Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells. Development 133: 2627-38 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Djagaeva I et al. (2005) Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis. Dev Biol 284: 143-56 PubMed GONUTS page
  7. 7.0 7.1 Dodson GS et al. (1998) Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis. Development 125: 2883-92 PubMed GONUTS page
  8. Thomas JH & Wieschaus E (2004) src64 and tec29 are required for microfilament contraction during Drosophila cellularization. Development 131: 863-71 PubMed GONUTS page
  9. Harris KE & Beckendorf SK (2007) Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration. Development 134: 2017-25 PubMed GONUTS page
  10. 10.0 10.1 Dubnau J et al. (2003) The staufen/pumilio pathway is involved in Drosophila long-term memory. Curr Biol 13: 286-96 PubMed GONUTS page
  11. 11.0 11.1 11.2 Kelso RJ et al. (2002) Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylation. J Cell Biol 156: 703-13 PubMed GONUTS page
  12. Nicolaï M et al. (2003) Gain-of-function screen identifies a role of the Src64 oncogene in Drosophila mushroom body development. J Neurobiol 57: 291-302 PubMed GONUTS page
  13. Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
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