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FB:Sod

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Sod ( synonyms: CG11793, Complementation group G, Cu, Zn superoxide dismutase, Cu,Zn Sod, Cu,Zn-SOD, Cu-Zn SOD, Cu-Zn superoxide dismutase, Cu/Zn SOD, Cu/Zn sod, Cu/Zn superoxide dismutase, Cu/Zn-Superoxide dismutase, Cu/ZnSOD, CuSOD, CuZn SOD, CuZn superoxide dismutase, CuZn-SOD, CuZn-SOD1, CuZn-superoxide dismutase, CuZn-superoxide dismutase (SOD)1, CuZnSOD, Cu(2+) Zn(2+) superoxide dismutase, Cu(2+)/Zn(2+)SOD, Cu(2+)Zn(2+) superoxide dismutase, G, Mn SOD, Mn superoxide dismutase, SOD, SOD-1, SOD1, Sod-1, Sod1, Superoxidase dismutase, Superoxide dismutase 1, Tetrazolium oxidase, To, To-1, ZnSod, cSOD, cSod, copper-zinc superoxide, copper-zinc superoxide dismutase, cytoplasmic Cu/ZnSOD, dSOD1, dismutase, l(3)108, l(3)68Af', l(3)G, sod, sod1, super oxide dismutase, superoxide dismutase, superoxide dismutase 1, superoxide dismutatase, superoxide-dismutase, superoxido dismutase, tetrazolium oxidase-1 )
Protein Name(s) Superoxide dismutase,
External Links
FB FBgn0003462

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004784

superoxide dismutase activity

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0004784

superoxide dismutase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR018152

F

From FB

GO:0005737

cytoplasm

FB:FBrf0123320

NAS: Non-traceable Author Statement

C

From FB

GO:0006801

superoxide metabolic process

FB:FBrf0123320

NAS: Non-traceable Author Statement

P

From FB

GO:0006801

superoxide metabolic process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001424
InterPro:IPR024134

P

From FB

GO:0006979

response to oxidative stress

FB:FBrf0204928
PMID:18508973[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007568

aging

FB:FBrf0157351
PMID:11707917[2]

TAS: Traceable Author Statement

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0105941
PMID:9858546[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0125364
PMID:10638521[4]

TAS: Traceable Author Statement

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0135874
PMID:11348656[5]

TAS: Traceable Author Statement

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0141394
PMID:11707932[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0155558
PMID:12539239[7]

TAS: Traceable Author Statement

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0155931
PMID:12470891[8]

TAS: Traceable Author Statement

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0156109
PMID:11998690[9]

TAS: Traceable Author Statement

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0204928
PMID:18508973[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016209

antioxidant activity

FB:FBrf0155558
PMID:12539239[7]

NAS: Non-traceable Author Statement

F

From FB

GO:0019430

removal of superoxide radicals

FB:FBrf0105495

NAS: Non-traceable Author Statement

P

From FB

GO:0046872

metal ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001424

F

From FB

GO:0055114

oxidation-reduction process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001424
InterPro:IPR018152
InterPro:IPR024134

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ruan H & Wu CF (2008) Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A 105: 7506-10 PubMed GONUTS page
  2. Luckinbill LS & Foley P (2000) Experimental and empirical approaches in the study of aging. Biogerontology 1: 3-13 PubMed GONUTS page
  3. Sun J & Tower J (1999) FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol Cell Biol 19: 216-28 PubMed GONUTS page
  4. Longo VD (1999) Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells. Neurobiol Aging 20: 479-86 PubMed GONUTS page
  5. Boulianne GL (2001) Neuronal regulation of lifespan: clues from flies and worms. Mech Ageing Dev 122: 883-94 PubMed GONUTS page
  6. Rogina B & Helfand SL (2000) Cu, Zn superoxide dismutase deficiency accelerates the time course of an age-related marker in Drosophila melanogaster. Biogerontology 1: 163-9 PubMed GONUTS page
  7. 7.0 7.1 Helfand SL & Rogina B (2003) Molecular genetics of aging in the fly: is this the end of the beginning? Bioessays 25: 134-41 PubMed GONUTS page
  8. Aigaki T et al. (2002) Longevity determination genes in Drosophila melanogaster. Mech Ageing Dev 123: 1531-41 PubMed GONUTS page
  9. Wolkow CA (2002) Life span: getting the signal from the nervous system. Trends Neurosci 25: 212-6 PubMed GONUTS page
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