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FB:Sin3A

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Sin3A ( synonyms: 159A11T, 27/3, 97/15, CG8815, ES2-3, ESTS:159A11T, EY2-9, Enhancer of GMR-sina 2-3, SIN3, SIN3A, Sin 3A, Sin3, Sin3a, dSin3, dSin3A, l(2)08269, l(2)k02703, l(2)k05415, l(2)k09715, ld, sin3, sin3A, sni3 )
Protein Name(s) Sin3A,
External Links
FB FBgn0022764

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000785

chromatin

FB:FBrf0132059
PMID:11080159[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0000791

euchromatin

FB:FBrf0162185
PMID:12865422[2]

TAS: Traceable Author Statement

C

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0005364

F

From FB

GO:0003712

transcription cofactor activity

FB:FBrf0157326

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0005364

C

From FB

GO:0005634

nucleus

FB:FBrf0118799

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0132059
PMID:11080159[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0206103
PMID:18816856[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0211588
PMID:20566628[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0211659
PMID:18535655[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0005364

P

From FB

GO:0007346

regulation of mitotic cell cycle

FB:FBrf0149111
PMID:12077326[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0131381
PMID:11102367[7]

TAS: Traceable Author Statement

P

From FB

GO:0007517

muscle organ development

FB:FBrf0190556
PMID:16547170[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016580

Sin3 complex

FB:FBrf0162185
PMID:12865422[2]

NAS: Non-traceable Author Statement

C

From FB

GO:0017053

transcriptional repressor complex

FB:FBrf0211588
PMID:20566628[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0129910
PMID:10920384[9]

TAS: Traceable Author Statement

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0132059
PMID:11080159[1]

IEP: Inferred from Expression Pattern

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0162185
PMID:12865422[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0188108
PMID:16055719[10]

IPI: Inferred from Physical Interaction

FB:FBgn0023215

F

From FB

GO:0048666

neuron development

FB:FBrf0190556
PMID:16547170[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0070822

Sin3-type complex

FB:FBrf0211588
PMID:20566628[4]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Pile LA & Wassarman DA (2000) Chromosomal localization links the SIN3-RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression. EMBO J 19: 6131-40 PubMed GONUTS page
  2. 2.0 2.1 2.2 Pile LA et al. (2003) The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. J Biol Chem 278: 37840-8 PubMed GONUTS page
  3. Sharma V et al. (2008) Drosophila SIN3 is required at multiple stages of development. Dev Dyn 237: 3040-50 PubMed GONUTS page
  4. 4.0 4.1 4.2 Spain MM et al. (2010) Drosophila SIN3 isoforms interact with distinct proteins and have unique biological functions. J Biol Chem 285: 27457-67 PubMed GONUTS page
  5. Burgio G et al. (2008) Genetic identification of a network of factors that functionally interact with the nucleosome remodeling ATPase ISWI. PLoS Genet 4: e1000089 PubMed GONUTS page
  6. Pile LA et al. (2002) The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels. Mol Cell Biol 22: 4965-76 PubMed GONUTS page
  7. Prokopenko SN et al. (2000) Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics 156: 1691-715 PubMed GONUTS page
  8. 8.0 8.1 8.2 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
  9. Kozlova T & Thummel CS (2000) Steroid regulation of postembryonic development and reproduction in Drosophila. Trends Endocrinol Metab 11: 276-80 PubMed GONUTS page
  10. Loo LW et al. (2005) The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster. Mol Cell Biol 25: 7078-91 PubMed GONUTS page
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