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FB:Sin3A
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Sin3A ( synonyms: 159A11T, 27/3, 97/15, CG8815, ES2-3, ESTS:159A11T, EY2-9, Enhancer of GMR-sina 2-3, SIN3, SIN3A, Sin 3A, Sin3, Sin3a, dSin3, dSin3A, l(2)08269, l(2)k02703, l(2)k05415, l(2)k09715, ld, sin3, sin3A, sni3 ) | |
| Protein Name(s) | Sin3A, | |
| External Links | ||
| FB | FBgn0022764 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000785 |
chromatin |
FB:FBrf0132059 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0000791 |
euchromatin |
FB:FBrf0162185 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0005364 |
F |
From FB |
||
| GO:0003712 |
transcription cofactor activity |
FB:FBrf0157326 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0005364 |
C |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0118799 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0132059 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0206103 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005700 |
polytene chromosome |
FB:FBrf0211588 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005700 |
polytene chromosome |
FB:FBrf0211659 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0005364 |
P |
From FB |
||
| GO:0007346 |
regulation of mitotic cell cycle |
FB:FBrf0149111 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0131381 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016580 |
Sin3 complex |
FB:FBrf0162185 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0017053 |
transcriptional repressor complex |
FB:FBrf0211588 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0129910 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0132059 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0162185 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0188108 |
IPI: Inferred from Physical Interaction |
FB:FBgn0023215 |
F |
From FB |
||
| GO:0048666 |
neuron development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0070822 |
Sin3-type complex |
FB:FBrf0211588 |
IDA: Inferred from Direct Assay |
C |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Pile LA & Wassarman DA (2000) Chromosomal localization links the SIN3-RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression. EMBO J 19: 6131-40 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Pile LA et al. (2003) The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. J Biol Chem 278: 37840-8 PubMed GONUTS page
- ↑ Sharma V et al. (2008) Drosophila SIN3 is required at multiple stages of development. Dev Dyn 237: 3040-50 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Spain MM et al. (2010) Drosophila SIN3 isoforms interact with distinct proteins and have unique biological functions. J Biol Chem 285: 27457-67 PubMed GONUTS page
- ↑ Burgio G et al. (2008) Genetic identification of a network of factors that functionally interact with the nucleosome remodeling ATPase ISWI. PLoS Genet 4: e1000089 PubMed GONUTS page
- ↑ Pile LA et al. (2002) The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels. Mol Cell Biol 22: 4965-76 PubMed GONUTS page
- ↑ Prokopenko SN et al. (2000) Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics 156: 1691-715 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
- ↑ Kozlova T & Thummel CS (2000) Steroid regulation of postembryonic development and reproduction in Drosophila. Trends Endocrinol Metab 11: 276-80 PubMed GONUTS page
- ↑ Loo LW et al. (2005) The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster. Mol Cell Biol 25: 7078-91 PubMed GONUTS page