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FB:Ser
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Ser ( synonyms: Bd, Beaded, CG6127, CT18858, Ripped wing, Rpw, SER, dmSerrate, mel(3)8, ser, serrate, serratoid, std ) | |
| Protein Name(s) | Serrate, | |
| External Links | ||
| FB | FBgn0004197 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005102 |
receptor binding |
FB:FBrf0159232 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005112 |
Notch binding |
FB:FBrf0129916 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005112 |
Notch binding |
FB:FBrf0139594 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005112 |
Notch binding |
FB:FBrf0141518 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005112 |
Notch binding |
FB:FBrf0160750 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005112 |
Notch binding |
FB:FBrf0210603 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004647 |
F |
From FB |
||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005509 |
calcium ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0192221 |
IPI: Inferred from Physical Interaction |
FB:FBgn0036558 |
F |
From FB |
||
| GO:0005886 |
plasma membrane |
FB:FBrf0053814 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0123674 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0129916 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0141518 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0144824 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0187479 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007423 |
sensory organ development |
FB:FBrf0187479 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007431 |
salivary gland development |
FB:FBrf0159337 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0139594 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0160584 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007436 |
larval salivary gland morphogenesis |
FB:FBrf0160584 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007451 |
dorsal/ventral lineage restriction, imaginal disc |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0187469 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009986 |
cell surface |
FB:FBrf0210603 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0159232 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0016324 |
apical plasma membrane |
FB:FBrf0192221 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030673 |
axolemma |
FB:FBrf0053814 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030718 |
germ-line stem cell maintenance |
FB:FBrf0194773 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000463 |
P |
From FB |
||
| GO:0035017 |
cuticle pattern formation |
FB:FBrf0190179 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035167 |
larval lymph gland hemopoiesis |
FB:FBrf0155787 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0035170 |
lymph gland crystal cell differentiation |
FB:FBrf0167434 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035214 |
eye-antennal disc development |
FB:FBrf0192707 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0036011 |
imaginal disc-derived leg segmentation |
FB:FBrf0109019 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042688 |
crystal cell differentiation |
FB:FBrf0151854 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042688 |
crystal cell differentiation |
FB:FBrf0155787 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042688 |
crystal cell differentiation |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042689 |
regulation of crystal cell differentiation |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0192221 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046331 |
lateral inhibition |
FB:FBrf0187479 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0137174 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0192707 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 González-Gaitán M (2003) Signal dispersal and transduction through the endocytic pathway. Nat Rev Mol Cell Biol 4: 213-24 PubMed GONUTS page
- ↑ 2.0 2.1 Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
- ↑ 3.0 3.1 Bradley PL et al. (2001) Organ formation in Drosophila: specification and morphogenesis of the salivary gland. Bioessays 23: 901-11 PubMed GONUTS page
- ↑ 4.0 4.1 Sanson B (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2: 1083-8 PubMed GONUTS page
- ↑ López-Schier H (2003) The polarisation of the anteroposterior axis in Drosophila. Bioessays 25: 781-91 PubMed GONUTS page
- ↑ 6.0 6.1 Kim IM et al. (2010) Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand. Circ Res 106: 1233-43 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Glittenberg M et al. (2006) Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis. EMBO J 25: 4697-706 PubMed GONUTS page
- ↑ 8.0 8.1 Thomas U et al. (1991) The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs. Development 111: 749-61 PubMed GONUTS page
- ↑ Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Pitsouli C & Delidakis C (2005) The interplay between DSL proteins and ubiquitin ligases in Notch signaling. Development 132: 4041-50 PubMed GONUTS page
- ↑ Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
- ↑ 12.0 12.1 Haberman AS et al. (2003) Specification of cell fates within the salivary gland primordium. Dev Biol 258: 443-53 PubMed GONUTS page
- ↑ McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
- ↑ Lai EC et al. (2005) The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 132: 2319-32 PubMed GONUTS page
- ↑ Ward EJ et al. (2006) Stem cells signal to the niche through the Notch pathway in the Drosophila ovary. Curr Biol 16: 2352-8 PubMed GONUTS page
- ↑ Walters JW et al. (2005) Serrate-Notch signaling defines the scope of the initial denticle field by modulating EGFR activation. Dev Biol 286: 415-26 PubMed GONUTS page
- ↑ 17.0 17.1 Lebestky T et al. (2003) A Serrate-expressing signaling center controls Drosophila hematopoiesis. Genes Dev 17: 348-53 PubMed GONUTS page
- ↑ Meister M (2004) Blood cells of Drosophila: cell lineages and role in host defence. Curr Opin Immunol 16: 10-5 PubMed GONUTS page
- ↑ 19.0 19.1 Singh A et al. (2006) Lobe and Serrate are required for cell survival during early eye development in Drosophila. Development 133: 4771-81 PubMed GONUTS page
- ↑ Rauskolb C & Irvine KD (1999) Notch-mediated segmentation and growth control of the Drosophila leg. Dev Biol 210: 339-50 PubMed GONUTS page
- ↑ Duvic B et al. (2002) Notch signaling controls lineage specification during Drosophila larval hematopoiesis. Curr Biol 12: 1923-7 PubMed GONUTS page
- ↑ Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ Evans CJ & Banerjee U (2003) Transcriptional regulation of hematopoiesis in Drosophila. Blood Cells Mol Dis 30: 223-8 PubMed GONUTS page
- ↑ Gibson MC & Schubiger G (2001) Drosophila peripodial cells, more than meets the eye? Bioessays 23: 691-7 PubMed GONUTS page
