Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:Sec61alpha

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Sec61alpha ( synonyms: 0455, BEST:LD29847, BcDNA:LD29847, CG9539, DSec61alpha, E(br)165, LD29847, SEC61-alpha, SEC61ALPHA, Sec61, Sec61-alpha, Sec61a, anon-WO0118547.195, anon-WO0118547.277, dSec61alpha, endd2, l(2)k04917, sec61, sec61alpha )
Protein Name(s) Sec61alpha,
External Links
FB FBgn0086357

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005784

Sec61 translocon complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P38378

C

From FB

GO:0005791

rough endoplasmic reticulum

FB:FBrf0193935
PMID:17327273[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006616

SRP-dependent cotranslational protein targeting to membrane, translocation

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P38378

P

From FB

GO:0007391

dorsal closure

FB:FBrf0167639
PMID:14668390[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0210109
PMID:20112345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008219

cell death

FB:FBrf0146133

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008258

head involution

FB:FBrf0167639
PMID:14668390[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008565

protein transporter activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P38378

F

From FB

GO:0008565

protein transporter activity

FB:FBrf0141984

NAS: Non-traceable Author Statement

F

From FB

GO:0010507

negative regulation of autophagy

FB:FBrf0208155
PMID:19562034[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015450

P-P-bond-hydrolysis-driven protein transmembrane transporter activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002208

F

From FB

GO:0042335

cuticle development

FB:FBrf0167639
PMID:14668390[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045169

fusome

FB:FBrf0211303
PMID:18355804[5]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Röper K (2007) Rtnl1 is enriched in a specialized germline ER that associates with ribonucleoprotein granule components. J Cell Sci 120: 1081-92 PubMed GONUTS page
  2. 2.0 2.1 2.2 Ward RE et al. (2003) Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. Genetics 165: 1397-415 PubMed GONUTS page
  3. Wang X & Ward RE 4th (2010) Sec61alpha is required for dorsal closure during Drosophila embryogenesis through its regulation of Dpp signaling. Dev Dyn 239: 784-97 PubMed GONUTS page
  4. Arsham AM & Neufeld TP (2009) A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway. PLoS One 4: e6068 PubMed GONUTS page
  5. Lighthouse DV et al. (2008) New components of the Drosophila fusome suggest it plays novel roles in signaling and transport. Dev Biol 317: 59-71 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox