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FB:SPE
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | SPE ( synonyms: CG16705, CT37173, SP4, Sp4, Spatzle-processing enzyme, Spz-processing enzyme, c-SP4, proPO-AE, spe, spz processing enzyme ) | |
| Protein Name(s) | Spatzle-Processing Enzyme, | |
| External Links | ||
| FB | FBgn0039102 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004252 |
serine-type endopeptidase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:BAA34642 |
F |
From FB |
||
| GO:0004252 |
serine-type endopeptidase activity |
FB:FBrf0155784 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0006508 |
proteolysis |
FB:FBrf0155784 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006508 |
proteolysis |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0207060 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006959 |
humoral immune response |
FB:FBrf0212643 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006964 |
positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria |
FB:FBrf0192112 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0190205 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0192112 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0031638 |
zymogen activation |
FB:FBrf0190205 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045087 |
innate immune response |
FB:FBrf0190023 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045752 |
positive regulation of Toll signaling pathway |
FB:FBrf0190023 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050829 |
defense response to Gram-negative bacterium |
FB:FBrf0190023 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050829 |
defense response to Gram-negative bacterium |
FB:FBrf0190205 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050830 |
defense response to Gram-positive bacterium |
FB:FBrf0190023 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050832 |
defense response to fungus |
FB:FBrf0190023 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050832 |
defense response to fungus |
FB:FBrf0190205 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ross J et al. (2003) Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene 304: 117-31 PubMed GONUTS page
- ↑ El Chamy L et al. (2008) Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll. Nat Immunol 9: 1165-70 PubMed GONUTS page
- ↑ Paddibhatla I et al. (2010) Role for sumoylation in systemic inflammation and immune homeostasis in Drosophila larvae. PLoS Pathog 6: e1001234 PubMed GONUTS page
- ↑ 4.0 4.1 Mulinari S et al. (2006) Expression and regulation of Spätzle-processing enzyme in Drosophila. FEBS Lett 580: 5406-10 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Jang IH et al. (2006) A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. Dev Cell 10: 45-55 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 Kambris Z et al. (2006) Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. Curr Biol 16: 808-13 PubMed GONUTS page
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