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FB:SNF1A

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) SNF1A ( synonyms: 5'monophosphate-activated kinase, AMP-activated protein kinase, AMP-dependent kinase, AMPK, AMPKalpha, CG3051, DmAMPK alpha, EG:132E8.2, FBgn0023169, G protein-coupled receptor kinase 4, Gprk-4, Gprk4, SNF/AMP-activated protein S/T kinase gamma subunit, adenosine monophosphate-activated protein kinase, ampk, ampkalpha, dAMPKa, dAMPKalpha, snf1a )
Protein Name(s) SNF1A/AMP-activated protein kinase,
External Links
FB FBgn0023169

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000278

mitotic cell cycle

FB:FBrf0201353
PMID:17486097[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001558

regulation of cell growth

FB:FBrf0211348
PMID:20478298[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0161931

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004679

AMP-activated protein kinase activity

FB:FBrf0151783
PMID:12093363[4]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0004703

G-protein coupled receptor kinase activity

FB:FBrf0054946
PMID:1662381[5]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290
InterPro:IPR017441

F

From FB

GO:0005634

nucleus

FB:FBrf0151783
PMID:12093363[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0201625
PMID:17470638[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0054946
PMID:1662381[5]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0151783
PMID:12093363[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0161931

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006629

lipid metabolic process

FB:FBrf0211905
PMID:20862213[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007165

signal transduction

FB:FBrf0054946
PMID:1662381[5]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0009267

cellular response to starvation

FB:FBrf0211905
PMID:20862213[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030730

sequestering of triglyceride

FB:FBrf0211905
PMID:20862213[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031588

AMP-activated protein kinase complex

FB:FBrf0151783
PMID:12093363[4]

IC: Inferred by Curator

GO:0004679

C

From FB

GO:0042595

behavioral response to starvation

FB:FBrf0211905
PMID:20862213[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0044058

regulation of digestive system process

FB:FBrf0211348
PMID:20478298[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045197

establishment or maintenance of epithelial cell apical/basal polarity

FB:FBrf0201353
PMID:17486097[1]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lee JH et al. (2007) Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 447: 1017-20 PubMed GONUTS page
  2. 2.0 2.1 Bland ML et al. (2010) AMPK supports growth in Drosophila by regulating muscle activity and nutrient uptake in the gut. Dev Biol 344: 293-303 PubMed GONUTS page
  3. 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Pan DA & Hardie DG (2002) A homologue of AMP-activated protein kinase in Drosophila melanogaster is sensitive to AMP and is activated by ATP depletion. Biochem J 367: 179-86 PubMed GONUTS page
  5. 5.0 5.1 5.2 Cassill JA et al. (1991) Isolation of Drosophila genes encoding G protein-coupled receptor kinases. Proc Natl Acad Sci U S A 88: 11067-70 PubMed GONUTS page
  6. Mirouse V et al. (2007) LKB1 and AMPK maintain epithelial cell polarity under energetic stress. J Cell Biol 177: 387-92 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 Johnson EC et al. (2010) Altered metabolism and persistent starvation behaviors caused by reduced AMPK function in Drosophila. PLoS One 5: PubMed GONUTS page
  8. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
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