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FB:SCAR
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | SCAR ( synonyms: BEST:SD02991, CG4636, D-SCAR, DWave, DmSCAR, Dscar, SCAR/WAVE, Scar, Suppressor of cyclic AMP receptor, WAVE, Wave, dWAVE, l(2)k03107, l(2)k13811, scar, suppressor of cAR, wave ) | |
| Protein Name(s) | SCAR, | |
| External Links | ||
| FB | FBgn0041781 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000902 |
cell morphogenesis |
FB:FBrf0212211 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001745 |
compound eye morphogenesis |
FB:FBrf0144948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007010 |
cytoskeleton organization |
FB:FBrf0129344 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007030 |
Golgi organization |
FB:FBrf0213167 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007409 |
axonogenesis |
FB:FBrf0144948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007413 |
axonal fasciculation |
FB:FBrf0144948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007520 |
myoblast fusion |
FB:FBrf0201000 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007520 |
myoblast fusion |
FB:FBrf0204821 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0024273 |
P |
From FB |
||
| GO:0007520 |
myoblast fusion |
FB:FBrf0204821 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0243516 |
P |
From FB |
||
| GO:0007520 |
myoblast fusion |
FB:FBrf0204821 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008335 |
female germline ring canal stabilization |
FB:FBrf0144948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167406 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030029 |
actin filament-based process |
FB:FBrf0179496 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030031 |
cell projection assembly |
FB:FBrf0167406 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030036 |
actin cytoskeleton organization |
FB:FBrf0201000 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030037 |
actin filament reorganization involved in cell cycle |
FB:FBrf0144948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030866 |
cortical actin cytoskeleton organization |
FB:FBrf0167406 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0034314 |
Arp2/3 complex-mediated actin nucleation |
FB:FBrf0208460 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0060305 |
regulation of cell diameter |
FB:FBrf0213167 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ D'Ambrosio MV & Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191: 471-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Zallen JA et al. (2002) SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila. J Cell Biol 156: 689-701 PubMed GONUTS page
- ↑ Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 5.0 5.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ 6.0 6.1 Kondylis V et al. (2011) Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. PLoS One 6: e17173 PubMed GONUTS page
- ↑ 7.0 7.1 Richardson BE et al. (2007) SCAR/WAVE and Arp2/3 are crucial for cytoskeletal remodeling at the site of myoblast fusion. Development 134: 4357-67 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Berger S et al. (2008) WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion. J Cell Sci 121: 1303-13 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Kunda P et al. (2003) Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions. Curr Biol 13: 1867-75 PubMed GONUTS page
- ↑ Vartiainen MK & Machesky LM (2004) The WASP-Arp2/3 pathway: genetic insights. Curr Opin Cell Biol 16: 174-81 PubMed GONUTS page
- ↑ Liu R et al. (2009) Wash functions downstream of Rho and links linear and branched actin nucleation factors. Development 136: 2849-60 PubMed GONUTS page
