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FB:SAK
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | SAK ( synonyms: CG7186, PLK4, Plk4, SAK/PLK, SAK/PLK4, Sak, plk4, sak ) | |
| Protein Name(s) | Sak kinase, | |
| External Links | ||
| FB | FBgn0026371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0116278 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005814 |
centriole |
FB:FBrf0201218 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0116278 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007052 |
mitotic spindle organization |
FB:FBrf0200397 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007099 |
centriole replication |
FB:FBrf0189998 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007099 |
centriole replication |
FB:FBrf0201218 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007099 |
centriole replication |
FB:FBrf0206048 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007288 |
sperm axoneme assembly |
FB:FBrf0189998 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046599 |
regulation of centriole replication |
FB:FBrf0206754 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0051297 |
centrosome organization |
FB:FBrf0211489 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051298 |
centrosome duplication |
FB:FBrf0200397 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0005814 |
centriole |
FB:FBrf0200397 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 2.0 2.1 Peel N et al. (2007) Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation. Curr Biol 17: 834-43 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
- ↑ 4.0 4.1 Bettencourt-Dias M et al. (2005) SAK/PLK4 is required for centriole duplication and flagella development. Curr Biol 15: 2199-207 PubMed GONUTS page
- ↑ Dobbelaere J et al. (2008) A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol 6: e224 PubMed GONUTS page
- ↑ Rogers GC et al. (2009) The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication. J Cell Biol 184: 225-39 PubMed GONUTS page
- ↑ Blachon S et al. (2009) A proximal centriole-like structure is present in Drosophila spermatids and can serve as a model to study centriole duplication. Genetics 182: 133-44 PubMed GONUTS page
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