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FB:S6kII

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) S6kII ( synonyms: CG17596, RPS6-protein kinase-II, RSK, Ribosomal-S6-kinase, Rsk, S6 kinase II, S6KII, dRSK, ign, ignorant, p90 ribosomal S6 kinase, ribosomal-S6-kinase, rsk, rsk2 )
Protein Name(s) Ribosomal protein S6 kinase II,
External Links
FB FBgn0262866

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004674

protein serine/threonine kinase activity

FB:FBrf0132098
PMID:10908587[1]

NAS: Non-traceable Author Statement

F

From FB

GO:0004711

ribosomal protein S6 kinase activity

FB:FBrf0074759
PMID:8039719[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004711

ribosomal protein S6 kinase activity

FB:FBrf0121955

NAS: Non-traceable Author Statement

F

From FB

GO:0004711

ribosomal protein S6 kinase activity

FB:FBrf0194603
PMID:16763554[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0005515

protein binding

FB:FBrf0194603
PMID:16763554[3]

IPI: Inferred from Physical Interaction

FB:FBgn0003256

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR000961
InterPro:IPR002290
InterPro:IPR017441
InterPro:IPR017892

F

From FB

GO:0005840

ribosome

FB:FBrf0074759
PMID:8039719[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005840

ribosome

FB:FBrf0121955

NAS: Non-traceable Author Statement

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0074759
PMID:8039719[2]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR000961
InterPro:IPR002290
InterPro:IPR008271
InterPro:IPR017892

P

From FB

GO:0007474

imaginal disc-derived wing vein specification

FB:FBrf0194603
PMID:16763554[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007528

neuromuscular junction development

FB:FBrf0206691
PMID:19160443[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008306

associative learning

FB:FBrf0167437
PMID:14662373[5]

TAS: Traceable Author Statement

P

From FB

GO:0008306

associative learning

FB:FBrf0180431
PMID:15525759[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0194603
PMID:16763554[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031594

neuromuscular junction

FB:FBrf0206691
PMID:19160443[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0035106

operant conditioning

FB:FBrf0167437
PMID:14662373[5]

TAS: Traceable Author Statement

P

From FB

GO:0035106

operant conditioning

FB:FBrf0180431
PMID:15525759[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042308

negative regulation of protein import into nucleus

FB:FBrf0194603
PMID:16763554[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0042683

negative regulation of compound eye cone cell fate specification

FB:FBrf0194603
PMID:16763554[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045475

locomotor rhythm

FB:FBrf0206514
PMID:19144847[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046533

negative regulation of photoreceptor cell differentiation

FB:FBrf0194603
PMID:16763554[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046580

negative regulation of Ras protein signal transduction

FB:FBrf0194603
PMID:16763554[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0003079

P

From FB

GO:0046580

negative regulation of Ras protein signal transduction

FB:FBrf0194603
PMID:16763554[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0003205

P

From FB

GO:0050941

negative regulation of pigment cell differentiation

FB:FBrf0194603
PMID:16763554[3]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Wassarman DA et al. (1994) The Drosophila melanogaster ribosomal S6 kinase II-encoding sequence. Gene 144: 309-10 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 Kim M et al. (2006) Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development. EMBO J 25: 3056-67 PubMed GONUTS page
  4. 4.0 4.1 Fischer M et al. (2009) Drosophila RSK negatively regulates bouton number at the neuromuscular junction. Dev Neurobiol 69: 212-20 PubMed GONUTS page
  5. 5.0 5.1 Brembs B (2003) Operant conditioning in invertebrates. Curr Opin Neurobiol 13: 710-7 PubMed GONUTS page
  6. 6.0 6.1 Putz G et al. (2004) The S6KII (rsk) gene of Drosophila melanogaster differentially affects an operant and a classical learning task. J Neurosci 24: 9745-51 PubMed GONUTS page
  7. Akten B et al. (2009) Ribosomal s6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator. J Neurosci 29: 466-75 PubMed GONUTS page
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