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FB:Roc1b

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Roc1b ( synonyms: BcDNA:AT21612, CG16988, ROC1B, ROC1b, ROC2, Roc, dRoc1b, roc1b )
Protein Name(s) Roc1b,
External Links
FB FBgn0040291

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0148948
PMID:12062088[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0148948
PMID:12062088[1]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0005493

F

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0205823
PMID:18698375[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

FB:FBrf0202727
PMID:17880263[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0261268

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001841

F

From FB

GO:0016567

protein ubiquitination

FB:FBrf0148948
PMID:12062088[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0019005

SCF ubiquitin ligase complex

FB:FBrf0148948
PMID:12062088[1]

NAS: Non-traceable Author Statement

C

From FB

GO:0019915

lipid storage

FB:FBrf0206371
PMID:19067489[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0030317

sperm motility

FB:FBrf0180504
PMID:15331761[5]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Noureddine MA et al. (2002) Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase. Dev Cell 2: 757-70 PubMed GONUTS page
  2. Reynolds PJ et al. (2008) Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain swapping. PLoS One 3: e2918 PubMed GONUTS page
  3. Arama E et al. (2007) A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila. PLoS Biol 5: e251 PubMed GONUTS page
  4. Beller M et al. (2008) COPI complex is a regulator of lipid homeostasis. PLoS Biol 6: e292 PubMed GONUTS page
  5. Donaldson TD et al. (2004) Targeted disruption of Drosophila Roc1b reveals functional differences in the Roc subunit of Cullin-dependent E3 ubiquitin ligases. Mol Biol Cell 15: 4892-903 PubMed GONUTS page
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