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FB:RecQ4
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | RecQ4 ( synonyms: CG7487, DmRECQ4, RECQL4, cg7487, dRecQ4 ) | |
| Protein Name(s) | RecQ4, | |
| External Links | ||
| FB | FBgn0040290 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000739 |
DNA strand annealing activity |
FB:FBrf0209205 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0002164 |
larval development |
FB:FBrf0209176 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003678 |
DNA helicase activity |
FB:FBrf0130073 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004003 |
ATP-dependent DNA helicase activity |
FB:FBrf0209205 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0004386 |
helicase activity |
FB:FBrf0129923 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006260 |
DNA replication |
FB:FBrf0202953 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:9949 |
P |
From FB |
||
| GO:0006260 |
DNA replication |
FB:FBrf0209176 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006281 |
DNA repair |
FB:FBrf0202953 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:9949 |
P |
From FB |
||
| GO:0006284 |
base-excision repair |
FB:FBrf0208182 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006302 |
double-strand break repair |
FB:FBrf0208182 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006310 |
DNA recombination |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261530 |
P |
From FB |
||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007307 |
eggshell chorion gene amplification |
FB:FBrf0209176 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008094 |
DNA-dependent ATPase activity |
FB:FBrf0202953 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:9949 |
F |
From FB |
||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0208182 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010971 |
positive regulation of G2/M transition of mitotic cell cycle |
FB:FBrf0208182 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043138 |
3'-5' DNA helicase activity |
FB:FBrf0209205 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0045740 |
positive regulation of DNA replication |
FB:FBrf0208182 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0208182 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051301 |
cell division |
FB:FBrf0209176 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Capp C et al. (2009) Drosophila RecQ4 has a 3'-5' DNA helicase activity that is essential for viability. J Biol Chem 284: 30845-52 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Wu J et al. (2008) Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development. Dev Biol 323: 130-42 PubMed GONUTS page
- ↑ Sekelsky JJ et al. (2000) DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol 150: F31-6 PubMed GONUTS page
- ↑ Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Xu Y et al. (2009) dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila. PLoS One 4: e6107 PubMed GONUTS page
- ↑ 6.0 6.1 Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
