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FB:Rdl

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Rdl ( synonyms: CG10537, DmRDL, DmRdl, GABA, GABA receptor, GABA((A)), GABA((A)) receptor, GABAr, LCCH1, RDL, Rd1, Resistant to Dieldrin, gaba, rdl, resistance to dieldrin, resistant to dieldrin )
Protein Name(s) Resistant to dieldrin,
External Links
FB FBgn0004244

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004890

GABA-A receptor activity

FB:FBrf0113779

NAS: Non-traceable Author Statement

F

From FB

GO:0004890

GABA-A receptor activity

FB:FBrf0114947

NAS: Non-traceable Author Statement

F

From FB

GO:0004890

GABA-A receptor activity

FB:FBrf0123842

NAS: Non-traceable Author Statement

F

From FB

GO:0004890

GABA-A receptor activity

FB:FBrf0151774
PMID:12386938[1]

TAS: Traceable Author Statement

F

From FB

GO:0004890

GABA-A receptor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002289

F

From FB

GO:0005230

extracellular ligand-gated ion channel activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006202
InterPro:IPR018000

F

From FB

GO:0005886

plasma membrane

FB:FBrf0072817
PMID:8016117[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0006811

ion transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002289
InterPro:IPR006028
InterPro:IPR006029
InterPro:IPR006201
InterPro:IPR018000

P

From FB

GO:0009612

response to mechanical stimulus

FB:FBrf0192588
PMID:16943550[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0261794

P

From FB

GO:0016021

integral to membrane

FB:FBrf0123842

NAS: Non-traceable Author Statement

C

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006028
InterPro:IPR006201
InterPro:IPR018000

C

From FB

GO:0030424

axon

FB:FBrf0200439
PMID:18093529[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0030425

dendrite

FB:FBrf0200439
PMID:18093529[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0030431

sleep

FB:FBrf0206340
PMID:19038223[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042749

regulation of circadian sleep/wake cycle

FB:FBrf0207520
PMID:19230663[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045211

postsynaptic membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR018000

C

From FB

GO:0046682

response to cyclodiene

FB:FBrf0113779

NAS: Non-traceable Author Statement

P

From FB

GO:0046682

response to cyclodiene

FB:FBrf0114947

NAS: Non-traceable Author Statement

P

From FB

GO:0050805

negative regulation of synaptic transmission

FB:FBrf0160722
PMID:12805302[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0090328

regulation of olfactory learning

FB:FBrf0200439
PMID:18093529[4]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Towers PR & Sattelle DB (2002) A Drosophila melanogaster cell line (S2) facilitates post-genome functional analysis of receptors and ion channels. Bioessays 24: 1066-73 PubMed GONUTS page
  2. Chen R et al. (1994) Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor. Proc Natl Acad Sci U S A 91: 6069-73 PubMed GONUTS page
  3. Hekmat-Scafe DS et al. (2006) Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila. J Neurosci 26: 8943-54 PubMed GONUTS page
  4. 4.0 4.1 4.2 Liu X et al. (2007) GABAA receptor RDL inhibits Drosophila olfactory associative learning. Neuron 56: 1090-102 PubMed GONUTS page
  5. Parisky KM et al. (2008) PDF cells are a GABA-responsive wake-promoting component of the Drosophila sleep circuit. Neuron 60: 672-82 PubMed GONUTS page
  6. Chung BY et al. (2009) The GABA(A) receptor RDL acts in peptidergic PDF neurons to promote sleep in Drosophila. Curr Biol 19: 386-90 PubMed GONUTS page
  7. Lee D et al. (2003) GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons. J Neurosci 23: 4625-34 PubMed GONUTS page
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