FB:Ras85D

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Species (Taxon ID)	Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s)	Ras85D ( synonyms: C-ras1, CG9375, D-Ras, D-Ras1, D-ras-1, D-ras1, DRAS1, DRas, DRas85D/Ras, Dm Ras1, Dmras85D, Dras, Dras1, Dras85D, E(faf), E(sev)3C, EK3-4, Enhancer of faf, RAS, RAS1, RAS85D, RTK, Ras, Ras 85D, Ras GTPase, Ras oncogene at 85B, Ras-1, Ras1, Ras1/RAs85D, RasI, RasV12, Ras(V12), S35097, Su(tor)3-2, dRAS1, dRas, dRas1, dRas85D, dras1, fs(3)05703, l(3)06677, l(3)s1747, p21(Ras1), ras, ras 1, ras1, ras85B, ras85D )
Protein Name(s)	Ras oncogene at 85D,
External Links
FB	FBgn0003205

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000082	G1/S transition of mitotic cell cycle	FB:FBrf0141762 PMID:11735386^[1]	TAS: Traceable Author Statement		P	From FB
	GO:0001558	regulation of cell growth	FB:FBrf0141377 PMID:11782950^[2]	TAS: Traceable Author Statement		P	From FB
	GO:0001708	cell fate specification	FB:FBrf0139680 PMID:11606538^[3]	TAS: Traceable Author Statement		P	From FB
	GO:0002168	instar larval development	FB:FBrf0190001 PMID:16182526^[4]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0003924	GTPase activity	FB:FBrf0105495	ISS: Inferred from Sequence or Structural Similarity	MGI:MGI:96680	F	From FB
	GO:0003924	GTPase activity	FB:FBrf0123462	NAS: Non-traceable Author Statement		F	From FB
	GO:0003924	GTPase activity	FB:FBrf0173281 PMID:14579253^[5]	ISS: Inferred from Sequence or Structural Similarity		F	From FB
	GO:0005525	GTP binding	FB:FBrf0174215	IEA: Inferred from Electronic Annotation	InterPro:IPR001806 InterPro:IPR005225 InterPro:IPR020849	F	From FB
	GO:0005886	plasma membrane	FB:FBrf0207610 PMID:18503409^[6]	IDA: Inferred from Direct Assay		C	From FB
	GO:0005886	plasma membrane	FB:FBrf0210975	IDA: Inferred from Direct Assay		C	From FB
	GO:0006184	GTP catabolic process	FB:FBrf0174215	IEA: Inferred from Electronic Annotation	InterPro:IPR020849	P	From FB
	GO:0006606	protein import into nucleus	FB:FBrf0194603 PMID:16763554^[7]	IGI: Inferred from Genetic Interaction	FB:FBgn0003256	P	From FB
	GO:0006916	anti-apoptosis	FB:FBrf0144793 PMID:11832236^[8]	NAS: Non-traceable Author Statement		P	From FB
	GO:0007264	small GTPase mediated signal transduction	FB:FBrf0174215	IEA: Inferred from Electronic Annotation	InterPro:IPR001806	P	From FB
	GO:0007298	border follicle cell migration	FB:FBrf0128450 PMID:10822261^[9]	TAS: Traceable Author Statement		P	From FB
	GO:0007298	border follicle cell migration	FB:FBrf0132450 PMID:11141565^[10]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007309	oocyte axis specification	FB:FBrf0193906 PMID:16908845^[11]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007369	gastrulation	FB:FBrf0167479 PMID:14602078^[12]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007391	dorsal closure	FB:FBrf0151280 PMID:12147138^[13]	TAS: Traceable Author Statement		P	From FB
	GO:0007422	peripheral nervous system development	FB:FBrf0162204 PMID:12967983^[14]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007426	tracheal outgrowth, open tracheal system	FB:FBrf0190195 PMID:16326394^[15]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007428	primary branching, open tracheal system	FB:FBrf0167264 PMID:14570584^[16]	TAS: Traceable Author Statement		P	From FB
	GO:0007455	eye-antennal disc morphogenesis	FB:FBrf0192868 PMID:16963016^[17]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007472	wing disc morphogenesis	FB:FBrf0162081 PMID:12930782^[18]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007476	imaginal disc-derived wing morphogenesis	FB:FBrf0162081 PMID:12930782^[18]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007476	imaginal disc-derived wing morphogenesis	FB:FBrf0193945 PMID:16648592^[19]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0007507	heart development	FB:FBrf0151249 PMID:12027431^[20]	NAS: Non-traceable Author Statement		P	From FB
	GO:0007552	metamorphosis	FB:FBrf0209466 PMID:19965758^[21]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0008283	cell proliferation	FB:FBrf0194142 PMID:17082773^[22]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0008284	positive regulation of cell proliferation	FB:FBrf0206542 PMID:19141677^[23]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0008284	positive regulation of cell proliferation	FB:FBrf0212840 PMID:21176204^[24]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0008293	torso signaling pathway	FB:FBrf0111327 PMID:10494038^[25]	TAS: Traceable Author Statement		P	From FB
	GO:0008361	regulation of cell size	FB:FBrf0209242 PMID:19840402^[26]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0008595	anterior/posterior axis specification, embryo	FB:FBrf0111327 PMID:10494038^[25]	TAS: Traceable Author Statement		P	From FB
	GO:0016049	cell growth	FB:FBrf0141762 PMID:11735386^[1]	TAS: Traceable Author Statement		P	From FB
	GO:0019003	GDP binding	FB:FBrf0123462	NAS: Non-traceable Author Statement		F	From FB
	GO:0030307	positive regulation of cell growth	FB:FBrf0136845 PMID:11377964^[27]	TAS: Traceable Author Statement		P	From FB
	GO:0030307	positive regulation of cell growth	FB:FBrf0162295 PMID:13678953^[28]	TAS: Traceable Author Statement		P	From FB
	GO:0030381	chorion-containing eggshell pattern formation	FB:FBrf0139680 PMID:11606538^[3]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0030381	chorion-containing eggshell pattern formation	FB:FBrf0146988 PMID:11959829^[29]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0030707	ovarian follicle cell development	FB:FBrf0128450 PMID:10822261^[9]	TAS: Traceable Author Statement		P	From FB
	GO:0035088	establishment or maintenance of apical/basal cell polarity	FB:FBrf0193906 PMID:16908845^[11]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0035099	hemocyte migration	FB:FBrf0146914 PMID:11955438^[30]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0040008	regulation of growth	FB:FBrf0130003 PMID:11128988^[31]	TAS: Traceable Author Statement		P	From FB
	GO:0040008	regulation of growth	FB:FBrf0167548 PMID:14592975^[32]	IGI: Inferred from Genetic Interaction	FB:FBgn0263289	P	From FB
	GO:0040008	regulation of growth	FB:FBrf0167548 PMID:14592975^[32]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0040014	regulation of multicellular organism growth	FB:FBrf0190001 PMID:16182526^[4]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0042066	perineurial glial growth	FB:FBrf0145861	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0043066	negative regulation of apoptotic process	FB:FBrf0193620 PMID:17055987^[33]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0043066	negative regulation of apoptotic process	FB:FBrf0209242 PMID:19840402^[26]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0045500	sevenless signaling pathway	FB:FBrf0129916 PMID:10929403^[34]	TAS: Traceable Author Statement		P	From FB
	GO:0045610	regulation of hemocyte differentiation	FB:FBrf0180639 PMID:15381778^[35]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0046534	positive regulation of photoreceptor cell differentiation	FB:FBrf0194603 PMID:16763554^[7]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0046673	negative regulation of compound eye retinal cell programmed cell death	FB:FBrf0147184 PMID:12006672^[36]	TAS: Traceable Author Statement		P	From FB
	GO:0046673	negative regulation of compound eye retinal cell programmed cell death	FB:FBrf0156100 PMID:12547518^[37]	TAS: Traceable Author Statement		P	From FB
	GO:0046673	negative regulation of compound eye retinal cell programmed cell death	FB:FBrf0180487 PMID:15511643^[38]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0048749	compound eye development	FB:FBrf0135730 PMID:11290305^[39]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0048749	compound eye development	FB:FBrf0212407 PMID:20937772^[40]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0048863	stem cell differentiation	FB:FBrf0211181 PMID:20432470^[41]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0048865	stem cell fate commitment	FB:FBrf0210887 PMID:20463031^[42]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0072002	Malpighian tubule development	FB:FBrf0211181 PMID:20432470^[41]	IMP: Inferred from Mutant Phenotype		P	From FB
	GO:0072089	stem cell proliferation	FB:FBrf0211181 PMID:20432470^[41]	IMP: Inferred from Mutant Phenotype		P	From FB
NOT	GO:0046664	dorsal closure, amnioserosa morphology change	FB:FBrf0147105 PMID:11973353^[43]	IMP: Inferred from Mutant Phenotype		P	From FB
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Baker NE (2001) Cell proliferation, survival, and death in the Drosophila eye. Semin Cell Dev Biol 12: 499-507 PubMed GONUTS page
↑ Johnston LA & Gallant P (2002) Control of growth and organ size in Drosophila. Bioessays 24: 54-64 PubMed GONUTS page
↑ ^3.0 ^3.1 Schnorr JD et al. (2001) Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis. Genetics 159: 609-22 PubMed GONUTS page
↑ ^4.0 ^4.1 Caldwell PE et al. (2005) Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr Biol 15: 1785-95 PubMed GONUTS page
↑ Jékely G (2003) Small GTPases and the evolution of the eukaryotic cell. Bioessays 25: 1129-38 PubMed GONUTS page
↑ Day JP et al. (2008) Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein. Biochem J 414: 363-74 PubMed GONUTS page
↑ ^7.0 ^7.1 Kim M et al. (2006) Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development. EMBO J 25: 3056-67 PubMed GONUTS page
↑ White K (2002) Signaling survival: how axons rescue their glia. Dev Cell 2: 128-30 PubMed GONUTS page
↑ ^9.0 ^9.1 Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
↑ Duchek P & Rørth P (2001) Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis. Science 291: 131-3 PubMed GONUTS page
↑ ^11.0 ^11.1 Poulton JS & Deng WM (2006) Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte. Proc Natl Acad Sci U S A 103: 12775-80 PubMed GONUTS page
↑ Li J et al. (2003) Coactivation of STAT and Ras is required for germ cell proliferation and invasive migration in Drosophila. Dev Cell 5: 787-98 PubMed GONUTS page
↑ Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
↑ Sepp KJ & Auld VJ (2003) Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development. J Neurosci 23: 8221-30 PubMed GONUTS page
↑ Cabernard C & Affolter M (2005) Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila. Dev Cell 9: 831-42 PubMed GONUTS page
↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
↑ Brown KE et al. (2006) Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway. Dev Biol 300: 710-21 PubMed GONUTS page
↑ ^18.0 ^18.1 Pallavi SK & Shashidhara LS (2003) Egfr/Ras pathway mediates interactions between peripodial and disc proper cells in Drosophila wing discs. Development 130: 4931-41 PubMed GONUTS page
↑ Dworkin I & Gibson G (2006) Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173: 1417-31 PubMed GONUTS page
↑ Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
↑ Rewitz KF et al. (2009) The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis. Science 326: 1403-5 PubMed GONUTS page
↑ Uhlirova M & Bohmann D (2006) JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. EMBO J 25: 5294-304 PubMed GONUTS page
↑ Jiang H & Edgar BA (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136: 483-93 PubMed GONUTS page
↑ Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page
↑ ^25.0 ^25.1 Baek KH & Lee KY (1999) Signal transduction pathway for anterior-posterior development in Drosophila. J Biomed Sci 6: 314-9 PubMed GONUTS page
↑ ^26.0 ^26.1 Wu Y et al. (2009) Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye. BMC Dev Biol 9: 53 PubMed GONUTS page
↑ Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
↑ Bergmann A & Lane ME (2003) HIDden targets of microRNAs for growth control. Trends Biochem Sci 28: 461-3 PubMed GONUTS page
↑ James KE et al. (2002) Mosaic analyses reveal the function of Drosophila Ras in embryonic dorsoventral patterning and dorsal follicle cell morphogenesis. Development 129: 2209-22 PubMed GONUTS page
↑ Cho NK et al. (2002) Developmental control of blood cell migration by the Drosophila VEGF pathway. Cell 108: 865-76 PubMed GONUTS page
↑ Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page
↑ ^32.0 ^32.1 Brumby AM & Richardson HE (2003) scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J 22: 5769-79 PubMed GONUTS page
↑ Parker J (2006) Control of compartment size by an EGF ligand from neighboring cells. Curr Biol 16: 2058-65 PubMed GONUTS page
↑ Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
↑ Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page
↑ Gorski S & Marra M (2002) Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. Physiol Genomics 9: 59-69 PubMed GONUTS page
↑ Brachmann CB & Cagan RL (2003) Patterning the fly eye: the role of apoptosis. Trends Genet 19: 91-6 PubMed GONUTS page
↑ Cordero J et al. (2004) A role for wingless in an early pupal cell death event that contributes to patterning the Drosophila eye. Mech Dev 121: 1523-30 PubMed GONUTS page
↑ Halfar K et al. (2001) Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development 128: 1687-96 PubMed GONUTS page
↑ Sung PJ et al. (2010) Cytosolic Ras supports eye development in Drosophila. Mol Cell Biol 30: 5649-57 PubMed GONUTS page
↑ ^41.0 ^41.1 ^41.2 Zeng X et al. (2010) Tumor suppressors Sav/Scrib and oncogene Ras regulate stem-cell transformation in adult Drosophila malpighian tubules. J Cell Physiol 224: 766-74 PubMed GONUTS page
↑ Figeac N et al. (2010) Drosophila adult muscle precursors form a network of interconnected cells and are specified by the rhomboid-triggered EGF pathway. Development 137: 1965-73 PubMed GONUTS page
↑ Harden N et al. (2002) Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila. J Cell Sci 115: 2119-29 PubMed GONUTS page

[PMID:11735386-0] 1.0 ^1.1 Baker NE (2001) Cell proliferation, survival, and death in the Drosophila eye. Semin Cell Dev Biol 12: 499-507 PubMed GONUTS page

[PMID:11782950-1] Johnston LA & Gallant P (2002) Control of growth and organ size in Drosophila. Bioessays 24: 54-64 PubMed GONUTS page

[PMID:11606538-2] 3.0 ^3.1 Schnorr JD et al. (2001) Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis. Genetics 159: 609-22 PubMed GONUTS page

[PMID:16182526-3] 4.0 ^4.1 Caldwell PE et al. (2005) Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr Biol 15: 1785-95 PubMed GONUTS page

[PMID:14579253-4] Jékely G (2003) Small GTPases and the evolution of the eukaryotic cell. Bioessays 25: 1129-38 PubMed GONUTS page

[PMID:18503409-5] Day JP et al. (2008) Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein. Biochem J 414: 363-74 PubMed GONUTS page

[PMID:16763554-6] 7.0 ^7.1 Kim M et al. (2006) Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development. EMBO J 25: 3056-67 PubMed GONUTS page

[PMID:11832236-7] White K (2002) Signaling survival: how axons rescue their glia. Dev Cell 2: 128-30 PubMed GONUTS page

[PMID:10822261-8] 9.0 ^9.1 Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page

[PMID:11141565-9] Duchek P & Rørth P (2001) Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis. Science 291: 131-3 PubMed GONUTS page

[PMID:16908845-10] 11.0 ^11.1 Poulton JS & Deng WM (2006) Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte. Proc Natl Acad Sci U S A 103: 12775-80 PubMed GONUTS page

[PMID:14602078-11] Li J et al. (2003) Coactivation of STAT and Ras is required for germ cell proliferation and invasive migration in Drosophila. Dev Cell 5: 787-98 PubMed GONUTS page

[PMID:12147138-12] Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page

[PMID:12967983-13] Sepp KJ & Auld VJ (2003) Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development. J Neurosci 23: 8221-30 PubMed GONUTS page

[PMID:16326394-14] Cabernard C & Affolter M (2005) Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila. Dev Cell 9: 831-42 PubMed GONUTS page

[PMID:14570584-15] Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page

[PMID:16963016-16] Brown KE et al. (2006) Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway. Dev Biol 300: 710-21 PubMed GONUTS page

[PMID:12930782-17] 18.0 ^18.1 Pallavi SK & Shashidhara LS (2003) Egfr/Ras pathway mediates interactions between peripodial and disc proper cells in Drosophila wing discs. Development 130: 4931-41 PubMed GONUTS page

[PMID:16648592-18] Dworkin I & Gibson G (2006) Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173: 1417-31 PubMed GONUTS page

[PMID:12027431-19] Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page

[PMID:19965758-20] Rewitz KF et al. (2009) The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis. Science 326: 1403-5 PubMed GONUTS page

[PMID:17082773-21] Uhlirova M & Bohmann D (2006) JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. EMBO J 25: 5294-304 PubMed GONUTS page

[PMID:19141677-22] Jiang H & Edgar BA (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136: 483-93 PubMed GONUTS page

[PMID:21176204-23] Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page

[PMID:10494038-24] 25.0 ^25.1 Baek KH & Lee KY (1999) Signal transduction pathway for anterior-posterior development in Drosophila. J Biomed Sci 6: 314-9 PubMed GONUTS page

[PMID:19840402-25] 26.0 ^26.1 Wu Y et al. (2009) Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye. BMC Dev Biol 9: 53 PubMed GONUTS page

[PMID:11377964-26] Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page

[PMID:13678953-27] Bergmann A & Lane ME (2003) HIDden targets of microRNAs for growth control. Trends Biochem Sci 28: 461-3 PubMed GONUTS page

[PMID:11959829-28] James KE et al. (2002) Mosaic analyses reveal the function of Drosophila Ras in embryonic dorsoventral patterning and dorsal follicle cell morphogenesis. Development 129: 2209-22 PubMed GONUTS page

[PMID:11955438-29] Cho NK et al. (2002) Developmental control of blood cell migration by the Drosophila VEGF pathway. Cell 108: 865-76 PubMed GONUTS page

[PMID:11128988-30] Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page

[PMID:14592975-31] 32.0 ^32.1 Brumby AM & Richardson HE (2003) scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J 22: 5769-79 PubMed GONUTS page

[PMID:17055987-32] Parker J (2006) Control of compartment size by an EGF ligand from neighboring cells. Curr Biol 16: 2058-65 PubMed GONUTS page

[PMID:10929403-33] Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page

[PMID:15381778-34] Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page

[PMID:12006672-35] Gorski S & Marra M (2002) Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. Physiol Genomics 9: 59-69 PubMed GONUTS page

[PMID:12547518-36] Brachmann CB & Cagan RL (2003) Patterning the fly eye: the role of apoptosis. Trends Genet 19: 91-6 PubMed GONUTS page

[PMID:15511643-37] Cordero J et al. (2004) A role for wingless in an early pupal cell death event that contributes to patterning the Drosophila eye. Mech Dev 121: 1523-30 PubMed GONUTS page

[PMID:11290305-38] Halfar K et al. (2001) Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development 128: 1687-96 PubMed GONUTS page

[PMID:20937772-39] Sung PJ et al. (2010) Cytosolic Ras supports eye development in Drosophila. Mol Cell Biol 30: 5649-57 PubMed GONUTS page

[PMID:20432470-40] 41.0 ^41.1 ^41.2 Zeng X et al. (2010) Tumor suppressors Sav/Scrib and oncogene Ras regulate stem-cell transformation in adult Drosophila malpighian tubules. J Cell Physiol 224: 766-74 PubMed GONUTS page

[PMID:20463031-41] Figeac N et al. (2010) Drosophila adult muscle precursors form a network of interconnected cells and are specified by the rhomboid-triggered EGF pathway. Development 137: 1965-73 PubMed GONUTS page

[PMID:11973353-42] Harden N et al. (2002) Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila. J Cell Sci 115: 2119-29 PubMed GONUTS page

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FB:Ras85D

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h

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p

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