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FB:Rala
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Rala ( synonyms: CG2849, D-RalA, DRal, DRala, Dm RalA, Dral, DralA, Drala, RALA, Ral, Ral-a, RalA, anon-EST:fe1H4, anon-fast-evolving-1H4, dRal, l(1)G0174, l(1)G0373, l(1)G0501, ral, ralA ) | |
| Protein Name(s) | Ras-related protein, | |
| External Links | ||
| FB | FBgn0015286 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003924 |
GTPase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003924 |
GTPase activity |
FB:FBrf0110725 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003924 |
GTPase activity |
FB:FBrf0124068 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003924 |
GTPase activity |
FB:FBrf0173281 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005525 |
GTP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0205307 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006184 |
GTP catabolic process |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0205307 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0151280 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007464 |
R3/R4 cell fate commitment |
FB:FBrf0213208 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008593 |
regulation of Notch signaling pathway |
FB:FBrf0213208 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004647 |
P |
From FB |
||
| GO:0022604 |
regulation of cell morphogenesis |
FB:FBrf0110725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030165 |
PDZ domain binding |
FB:FBrf0161469 |
IPI: Inferred from Physical Interaction |
FB:FBgn0034590 |
F |
From FB |
||
| GO:0045087 |
innate immune response |
FB:FBrf0198620 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046329 |
negative regulation of JNK cascade |
FB:FBrf0110725 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000229 |
P |
From FB |
||
| GO:0046329 |
negative regulation of JNK cascade |
FB:FBrf0110725 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010303 |
P |
From FB |
||
| GO:0046329 |
negative regulation of JNK cascade |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Sawamoto K et al. (1999) The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway. J Cell Biol 146: 361-72 PubMed GONUTS page
- ↑ Jékely G (2003) Small GTPases and the evolution of the eukaryotic cell. Bioessays 25: 1129-38 PubMed GONUTS page
- ↑ 3.0 3.1 Ghiglione C et al. (2008) Drosophila RalA is essential for the maintenance of Jak/Stat signalling in ovarian follicles. EMBO Rep 9: 676-82 PubMed GONUTS page
- ↑ 4.0 4.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ 5.0 5.1 Cho B & Fischer JA (2011) Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activation. Development 138: 1349-59 PubMed GONUTS page
- ↑ Beller M et al. (2002) Identification and expression of Ima, a novel Ral-interacting Drosophila protein. Mech Dev 119 Suppl 1: S253-60 PubMed GONUTS page
- ↑ Chien Y et al. (2006) RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell 127: 157-70 PubMed GONUTS page
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