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FB:R

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) R ( synonyms: BEST:GH18528, C-ras3, CG1956, D-Rap1, DRap, DRap1, Dras3, Dras62B, E(faf), Enhancer of faf, RAP1, Rap, Rap1, Rap1 GTPase, Ras3, RasIII, l(3)62Bf, l(3)R, rap1, ras 3, ras3, roughened )
Protein Name(s) Roughened,
External Links
FB FBgn0004636

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001752

compound eye photoreceptor fate commitment

FB:FBrf0123461

NAS: Non-traceable Author Statement

P

From FB

GO:0003924

GTPase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0005627

F

From FB

GO:0005525

GTP binding

FB:FBrf0123461

NAS: Non-traceable Author Statement

F

From FB

GO:0005525

GTP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR005225
InterPro:IPR020849

F

From FB

GO:0005811

lipid particle

FB:FBrf0192764
PMID:16979555[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006184

GTP catabolic process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

P

From FB

GO:0006930

substrate-dependent cell migration, cell extension

FB:FBrf0192108
PMID:16818452[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007155

cell adhesion

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007264

small GTPase mediated signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001806

P

From FB

GO:0007391

dorsal closure

FB:FBrf0162150
PMID:14504224[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008360

regulation of cell shape

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016020

membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

C

From FB

GO:0016476

regulation of embryonic cell shape

FB:FBrf0192108
PMID:16818452[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0019003

GDP binding

FB:FBrf0123461

NAS: Non-traceable Author Statement

F

From FB

GO:0030713

ovarian follicle cell stalk formation

FB:FBrf0128450
PMID:10822261[5]

TAS: Traceable Author Statement

P

From FB

GO:0030718

germ-line stem cell maintenance

FB:FBrf0190226
PMID:16399083[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0021873

P

From FB

GO:0035099

hemocyte migration

FB:FBrf0192108
PMID:16818452[2]

IMP: Inferred from Mutant Phenotype

P

From FB

NOT

GO:0046328

regulation of JNK cascade

FB:FBrf0162150
PMID:14504224[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0000229

P

From FB

NOT

GO:0046328

regulation of JNK cascade

FB:FBrf0162150
PMID:14504224[4]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Cermelli S et al. (2006) The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr Biol 16: 1783-95 PubMed GONUTS page
  2. 2.0 2.1 2.2 Huelsmann S et al. (2006) The PDZ-GEF dizzy regulates cell shape of migrating macrophages via Rap1 and integrins in the Drosophila embryo. Development 133: 2915-24 PubMed GONUTS page
  3. 3.0 3.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
  4. 4.0 4.1 4.2 Boettner B et al. (2003) The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics 165: 159-69 PubMed GONUTS page
  5. Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
  6. Wang H et al. (2006) Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis. Dev Cell 10: 117-26 PubMed GONUTS page
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