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FB:Psn
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Psn ( synonyms: CG18803, CG5868, DPS, DPsn, DmPS, Dpresenilin, Dps, DrosPS, PS, PS1, dPresenilin, dPsn, l(3)77CDb, pre-senelin, pres, presenilin, psn ) | |
| Protein Name(s) | Presenilin, | |
| External Links | ||
| FB | FBgn0019947 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004190 |
aspartic-type endopeptidase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0141471 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0125466 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005938 |
cell cortex |
FB:FBrf0141471 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006509 |
membrane protein ectodomain proteolysis |
FB:FBrf0141674 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007010 |
cytoskeleton organization |
FB:FBrf0141471 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0194934 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007220 |
Notch receptor processing |
FB:FBrf0141674 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007220 |
Notch receptor processing |
FB:FBrf0184061 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008593 |
regulation of Notch signaling pathway |
FB:FBrf0214631 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016324 |
apical plasma membrane |
FB:FBrf0141674 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016337 |
cell-cell adhesion |
FB:FBrf0184061 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046331 |
lateral inhibition |
FB:FBrf0214518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0190133 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 López-Schier H & St Johnston D (2002) Drosophila nicastrin is essential for the intramembranous cleavage of notch. Dev Cell 2: 79-89 PubMed GONUTS page
- ↑ Nowotny P et al. (2000) Posttranslational modification and plasma membrane localization of the Drosophila melanogaster presenilin. Mol Cell Neurosci 15: 88-98 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Chung HM & Struhl G (2001) Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila. Nat Cell Biol 3: 1129-32 PubMed GONUTS page
- ↑ Seidner GA et al. (2006) Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila. Curr Biol 16: 1026-33 PubMed GONUTS page
- ↑ 5.0 5.1 Ahimou F et al. (2004) The adhesion force of Notch with Delta and the rate of Notch signaling. J Cell Biol 167: 1217-29 PubMed GONUTS page
- ↑ Wangler MF et al. (2011) Antioxidant proteins TSA and PAG interact synergistically with Presenilin to modulate Notch signaling in Drosophila. Protein Cell 2: 554-63 PubMed GONUTS page
- ↑ Koelzer S & Klein T (2006) Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless. Dev Biol 289: 77-90 PubMed GONUTS page
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