GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Pk92B
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Pk92B ( synonyms: ASK1, Apoptotic signal-regulating kinase 1, Ask1, CG4720, D-ASK, DASK, DASK1, DPk92B/ASK1, MEKK5/ASK1, dASK, dAsk1, pk92B ) | |
| Protein Name(s) | Protein kinase at 92B, | |
| External Links | ||
| FB | FBgn0014006 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004710 |
MAPK/ERK kinase kinase activity |
FB:FBrf0086676 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0086676 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0012501 |
programmed cell death |
FB:FBrf0154404 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0032874 |
positive regulation of stress-activated MAPK cascade |
FB:FBrf0189754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0032874 |
positive regulation of stress-activated MAPK cascade |
FB:FBrf0215011 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0032874 |
positive regulation of stress-activated MAPK cascade |
FB:FBrf0215011 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0215011 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048082 |
regulation of adult chitin-containing cuticle pigmentation |
FB:FBrf0215011 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 2.0 2.1 Wassarman DA et al. (1996) Pk92B: a Drosophila melanogaster protein kinase that belongs to the MEKK family. Gene 169: 283-4 PubMed GONUTS page
- ↑ Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Ryabinina OP et al. (2006) D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells. BMC Cell Biol 7: 7 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Sekine Y et al. (2011) p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors. J Cell Sci 124: 3006-16 PubMed GONUTS page
