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FB:Pi3K92E
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Pi3K92E ( synonyms: CG4141, Dmp110, Dp110, Dp110/PI3K, PI 3-kinase, PI(3)K, PI-3 kinase, PI-3-K, PI3 kinase, PI3'K, PI3-kinase, PI3K, PI3K-92D, PI3K-92E/Dp110, PI3K-Dp110, PI3K-dp110, PI3K92E, PI3k, PI((3))K, Phosphatidylinositol-3-kinase, Phosphoinositide-3 Kinase, Phosphotidylinositol 3 kinase, Pi3K, Pi3K92D, Pi3Kp110, anon-92Ed, class I PI(3)K, dP110, dPI 3-kinase, dPI3K, dp110, insulin-regulated PI3 kinase, p110, p110 PI3 kinase, p120, phosphatidylinositol 3-kinase, phospho-inositol-3 kinase at 92E, phosphoinositide 3-kinase, rea, type-1 PI3K ) | |
| Protein Name(s) | Pi3K92E, | |
| External Links | ||
| FB | FBgn0015279 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001727 |
lipid kinase activity |
FB:FBrf0193707 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0002164 |
larval development |
FB:FBrf0190035 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0002168 |
instar larval development |
FB:FBrf0190001 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005943 |
1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex |
FB:FBrf0091111 |
IPI: Inferred from Physical Interaction |
FB:FBgn0020622 |
C |
From FB |
||
| GO:0005943 |
1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex |
FB:FBrf0098471 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006914 |
autophagy |
FB:FBrf0180118 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006979 |
response to oxidative stress |
FB:FBrf0191581 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0194487 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007436 |
larval salivary gland morphogenesis |
FB:FBrf0187400 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007552 |
metamorphosis |
FB:FBrf0190035 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008286 |
insulin receptor signaling pathway |
FB:FBrf0141377 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008286 |
insulin receptor signaling pathway |
FB:FBrf0156191 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0111517 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0156191 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016049 |
cell growth |
FB:FBrf0156084 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016303 |
1-phosphatidylinositol-3-kinase activity |
FB:FBrf0091111 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0016303 |
1-phosphatidylinositol-3-kinase activity |
FB:FBrf0098471 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8975 |
F |
From FB |
||
| GO:0016303 |
1-phosphatidylinositol-3-kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0016310 |
phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0141377 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0162295 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030536 |
larval feeding behavior |
FB:FBrf0188283 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035004 |
phosphatidylinositol 3-kinase activity |
FB:FBrf0091111 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8975 |
F |
From FB |
||
| GO:0035004 |
phosphatidylinositol 3-kinase activity |
FB:FBrf0091111 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8976 |
F |
From FB |
||
| GO:0035004 |
phosphatidylinositol 3-kinase activity |
FB:FBrf0091111 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8977 |
F |
From FB |
||
| GO:0035004 |
phosphatidylinositol 3-kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
NCBI_NP:005017 |
F |
From FB |
||
| GO:0035005 |
1-phosphatidylinositol-4-phosphate 3-kinase activity |
FB:FBrf0091111 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0035005 |
1-phosphatidylinositol-4-phosphate 3-kinase activity |
FB:FBrf0098471 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8975 |
F |
From FB |
||
| GO:0040014 |
regulation of multicellular organism growth |
FB:FBrf0156191 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0040014 |
regulation of multicellular organism growth |
FB:FBrf0190001 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040014 |
regulation of multicellular organism growth |
FB:FBrf0190035 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042127 |
regulation of cell proliferation |
FB:FBrf0111517 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045572 |
positive regulation of imaginal disc growth |
FB:FBrf0091111 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045572 |
positive regulation of imaginal disc growth |
FB:FBrf0193707 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045727 |
positive regulation of translation |
FB:FBrf0202261 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0162295 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045927 |
positive regulation of growth |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046620 |
regulation of organ growth |
FB:FBrf0136845 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046620 |
regulation of organ growth |
FB:FBrf0156191 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0091111 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0125443 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0130065 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046854 |
phosphatidylinositol phosphorylation |
FB:FBrf0091111 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046854 |
phosphatidylinositol phosphorylation |
FB:FBrf0098471 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8975 |
P |
From FB |
||
| GO:0046854 |
phosphatidylinositol phosphorylation |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
FB:FBrf0091111 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
FB:FBrf0098471 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:8975 |
F |
From FB |
||
| GO:0048015 |
phosphatidylinositol-mediated signaling |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
FB:FBrf0193277 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0193707 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0193277 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0050773 |
regulation of dendrite development |
FB:FBrf0208858 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0055115 |
entry into diapause |
FB:FBrf0192255 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0060074 |
synapse maturation |
FB:FBrf0193277 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:2000377 |
regulation of reactive oxygen species metabolic process |
FB:FBrf0210161 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0013984 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Orme MH et al. (2006) Input from Ras is required for maximal PI(3)K signalling in Drosophila. Nat Cell Biol 8: 1298-302 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Mirth C et al. (2005) The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster. Curr Biol 15: 1796-807 PubMed GONUTS page
- ↑ 3.0 3.1 Caldwell PE et al. (2005) Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr Biol 15: 1785-95 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 Leevers SJ et al. (1996) The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J 15: 6584-94 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Vanhaesebroeck B et al. (1997) Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem Sci 22: 267-72 PubMed GONUTS page
- ↑ Rusten TE et al. (2004) Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. Dev Cell 7: 179-92 PubMed GONUTS page
- ↑ Yang Y et al. (2005) Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A 102: 13670-5 PubMed GONUTS page
- ↑ Herranz H et al. (2006) calderón encodes an organic cation transporter of the major facilitator superfamily required for cell growth and proliferation of Drosophila tissues. Development 133: 2617-25 PubMed GONUTS page
- ↑ Takeo S et al. (2005) Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog. Dev Biol 284: 204-18 PubMed GONUTS page
- ↑ 10.0 10.1 Johnston LA & Gallant P (2002) Control of growth and organ size in Drosophila. Bioessays 24: 54-64 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 Claeys I et al. (2002) Insulin-related peptides and their conserved signal transduction pathway. Peptides 23: 807-16 PubMed GONUTS page
- ↑ 12.0 12.1 Weinkove D et al. (1999) Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr Biol 9: 1019-29 PubMed GONUTS page
- ↑ Oldham S & Hafen E (2003) Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 13: 79-85 PubMed GONUTS page
- ↑ 14.0 14.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 15.0 15.1 Bergmann A & Lane ME (2003) HIDden targets of microRNAs for growth control. Trends Biochem Sci 28: 461-3 PubMed GONUTS page
- ↑ Wu Q et al. (2005) Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila. Proc Natl Acad Sci U S A 102: 13289-94 PubMed GONUTS page
- ↑ Hall DJ et al. (2007) Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila. BMC Biol 5: 10 PubMed GONUTS page
- ↑ 18.0 18.1 18.2 Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page
- ↑ Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ Weinkove D & Leevers SJ (2000) The genetic control of organ growth: insights from Drosophila. Curr Opin Genet Dev 10: 75-80 PubMed GONUTS page
- ↑ Scanga SE et al. (2000) The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila. Oncogene 19: 3971-7 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 Martín-Peña A et al. (2006) Age-independent synaptogenesis by phosphoinositide 3 kinase. J Neurosci 26: 10199-208 PubMed GONUTS page
- ↑ Parrish JZ et al. (2009) The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron 63: 788-802 PubMed GONUTS page
- ↑ Williams KD et al. (2006) Natural variation in Drosophila melanogaster diapause due to the insulin-regulated PI3-kinase. Proc Natl Acad Sci U S A 103: 15911-5 PubMed GONUTS page
- ↑ Lee JH et al. (2010) Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science 327: 1223-8 PubMed GONUTS page
