![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Pc
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Pc ( synonyms: CG32443, CG7618, DmPc, PC, Pc-G, PcG, dPC ) | |
| Protein Name(s) | Polycomb, | |
| External Links | ||
| FB | FBgn0003042 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000785 |
chromatin |
FB:FBrf0190604 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0000785 |
chromatin |
FB:FBrf0204496 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0003682 |
chromatin binding |
FB:FBrf0191372 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0173118 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0189910 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005725 |
intercalary heterochromatin |
FB:FBrf0173280 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005730 |
nucleolus |
FB:FBrf0190604 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005730 |
nucleolus |
FB:FBrf0204496 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006342 |
chromatin silencing |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006342 |
chromatin silencing |
FB:FBrf0123875 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0201535 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007385 |
specification of segmental identity, abdomen |
FB:FBrf0187379 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016322 |
neuron remodeling |
FB:FBrf0190330 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016458 |
gene silencing |
FB:FBrf0135809 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004861 |
P |
From FB |
||
| GO:0016458 |
gene silencing |
FB:FBrf0135809 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0202325 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035064 |
methylated histone residue binding |
FB:FBrf0151814 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0035064 |
methylated histone residue binding |
FB:FBrf0173275 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0035102 |
PRC1 complex |
FB:FBrf0131031 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0035102 |
PRC1 complex |
FB:FBrf0168050 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0035102 |
PRC1 complex |
FB:FBrf0173118 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035102 |
PRC1 complex |
FB:FBrf0183709 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0035186 |
syncytial blastoderm mitotic cell cycle |
FB:FBrf0190149 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Chen X et al. (2005) Tissue-specific TAFs counteract Polycomb to turn on terminal differentiation. Science 310: 869-72 PubMed GONUTS page
- ↑ Nègre N et al. (2006) Chromosomal distribution of PcG proteins during Drosophila development. PLoS Biol 4: e170 PubMed GONUTS page
- ↑ 3.0 3.1 Mulholland NM et al. (2003) Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA. Genes Dev 17: 2741-6 PubMed GONUTS page
- ↑ Grimaud C et al. (2006) RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124: 957-71 PubMed GONUTS page
- ↑ Zhimulev IF & Belyaeva ES (2003) Intercalary heterochromatin and genetic silencing. Bioessays 25: 1040-51 PubMed GONUTS page
- ↑ Goodliffe JM et al. (2007) Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1. BMC Mol Biol 8: 40 PubMed GONUTS page
- ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
- ↑ Wang J et al. (2006) Steroid hormone-dependent transformation of polyhomeotic mutant neurons in the Drosophila brain. Development 133: 1231-40 PubMed GONUTS page
- ↑ 9.0 9.1 Roseman RR et al. (2001) Long-range repression by multiple polycomb group (PcG) proteins targeted by fusion to a defined DNA-binding domain in Drosophila. Genetics 158: 291-307 PubMed GONUTS page
- ↑ Bello B et al. (2007) Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of Drosophila. Development 134: 1091-9 PubMed GONUTS page
- ↑ Czermin B et al. (2002) Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111: 185-96 PubMed GONUTS page
- ↑ Ahringer J (2000) NuRD and SIN3 histone deacetylase complexes in development. Trends Genet 16: 351-6 PubMed GONUTS page
- ↑ Lehmann M (2004) Anything else but GAGA: a nonhistone protein complex reshapes chromatin structure. Trends Genet 20: 15-22 PubMed GONUTS page
- ↑ Levine SS et al. (2004) Division of labor in polycomb group repression. Trends Biochem Sci 29: 478-85 PubMed GONUTS page
- ↑ O'Dor E et al. (2006) Polycomb group mutants exhibit mitotic defects in syncytial cell cycles of Drosophila embryos. Dev Biol 290: 312-22 PubMed GONUTS page
cgi |
mn |
prs |