Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:Nrx-IV

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Nrx-IV ( synonyms: CG6827, CT21123, Dnrx, NRX, NRX IV, Neurexin, Neurexin 4, Neurexin-4, Neurexin-IV, NeurexinIV, Nrx, Nrx IV, NrxIV, Nx IV, l(3)68Ff, l(3)rsg23, neurexin, neurexin IV, neurexinIV, nrx, nrx IV, nrx-IV, nrxIV, rose-gespleten region interval 23, rsg23 )
Protein Name(s) Neurexin IV,
External Links
FB FBgn0013997

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004888

transmembrane signaling receptor activity

FB:FBrf0141274

ISS: Inferred from Sequence or Structural Similarity

NCBI_NP:054860

F

From FB

GO:0005886

plasma membrane

FB:FBrf0091013
PMID:8978610[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005886

plasma membrane

FB:FBrf0210975

IDA: Inferred from Direct Assay

C

From FB

GO:0005887

integral to plasma membrane

FB:FBrf0151280
PMID:12147138[2]

NAS: Non-traceable Author Statement

C

From FB

GO:0005918

septate junction

FB:FBrf0110443
PMID:10449347[3]

TAS: Traceable Author Statement

C

From FB

GO:0005918

septate junction

FB:FBrf0141282
PMID:11700298[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0005918

septate junction

FB:FBrf0151280
PMID:12147138[2]

NAS: Non-traceable Author Statement

C

From FB

GO:0005918

septate junction

FB:FBrf0155581
PMID:12500938[5]

TAS: Traceable Author Statement

C

From FB

GO:0005918

septate junction

FB:FBrf0159315
PMID:12565697[6]

TAS: Traceable Author Statement

C

From FB

GO:0005918

septate junction

FB:FBrf0159915
PMID:12766944[7]

TAS: Traceable Author Statement

C

From FB

GO:0005919

pleated septate junction

FB:FBrf0180155
PMID:15459097[8]

IDA: Inferred from Direct Assay

C

From FB

GO:0007155

cell adhesion

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000421

P

From FB

GO:0007163

establishment or maintenance of cell polarity

FB:FBrf0159915
PMID:12766944[7]

NAS: Non-traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0110443
PMID:10449347[3]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0141282
PMID:11700298[4]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0160929
PMID:12782681[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008065

establishment of blood-nerve barrier

FB:FBrf0151111

NAS: Non-traceable Author Statement

P

From FB

GO:0008104

protein localization

FB:FBrf0110443
PMID:10449347[3]

TAS: Traceable Author Statement

P

From FB

GO:0008104

protein localization

FB:FBrf0159315
PMID:12565697[6]

TAS: Traceable Author Statement

P

From FB

GO:0008366

axon ensheathment

FB:FBrf0191040
PMID:16554482[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016021

integral to membrane

FB:FBrf0151111

NAS: Non-traceable Author Statement

C

From FB

GO:0016080

synaptic vesicle targeting

FB:FBrf0127207
PMID:10798391[11]

NAS: Non-traceable Author Statement

P

From FB

GO:0016081

synaptic vesicle docking involved in exocytosis

FB:FBrf0127207
PMID:10798391[11]

NAS: Non-traceable Author Statement

P

From FB

GO:0019991

septate junction assembly

FB:FBrf0151111

NAS: Non-traceable Author Statement

P

From FB

GO:0019991

septate junction assembly

FB:FBrf0191040
PMID:16554482[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0021682

nerve maturation

FB:FBrf0191040
PMID:16554482[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035151

regulation of tube size, open tracheal system

FB:FBrf0162083
PMID:12930776[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045216

cell-cell junction organization

FB:FBrf0151280
PMID:12147138[2]

TAS: Traceable Author Statement

P

From FB

GO:0060857

establishment of glial blood-brain barrier

FB:FBrf0189922
PMID:16213218[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0060857

establishment of glial blood-brain barrier

FB:FBrf0202685
PMID:18199760[14]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Baumgartner S et al. (1996) A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function. Cell 87: 1059-68 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  3. 3.0 3.1 3.2 Noselli S & Agnès F (1999) Roles of the JNK signaling pathway in Drosophila morphogenesis. Curr Opin Genet Dev 9: 466-72 PubMed GONUTS page
  4. 4.0 4.1 Tepass U et al. (2001) Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet 35: 747-84 PubMed GONUTS page
  5. Médina E et al. (2002) Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells. Biol Cell 94: 305-13 PubMed GONUTS page
  6. 6.0 6.1 Cereijido M et al. (2003) Membrane targeting. Prog Biophys Mol Biol 81: 81-115 PubMed GONUTS page
  7. 7.0 7.1 Humbert P et al. (2003) Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. Bioessays 25: 542-53 PubMed GONUTS page
  8. Faivre-Sarrailh C et al. (2004) Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function. Development 131: 4931-42 PubMed GONUTS page
  9. Schulte J et al. (2003) Gliotactin, a novel marker of tricellular junctions, is necessary for septate junction development in Drosophila. J Cell Biol 161: 991-1000 PubMed GONUTS page
  10. 10.0 10.1 10.2 Banerjee S et al. (2006) Axonal ensheathment and septate junction formation in the peripheral nervous system of Drosophila. J Neurosci 26: 3319-29 PubMed GONUTS page
  11. 11.0 11.1 Lloyd TE et al. (2000) A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron 26: 45-50 PubMed GONUTS page
  12. Paul SM et al. (2003) The Na+/K+ ATPase is required for septate junction function and epithelial tube-size control in the Drosophila tracheal system. Development 130: 4963-74 PubMed GONUTS page
  13. Schwabe T et al. (2005) GPCR signaling is required for blood-brain barrier formation in drosophila. Cell 123: 133-44 PubMed GONUTS page
  14. Stork T et al. (2008) Organization and function of the blood-brain barrier in Drosophila. J Neurosci 28: 587-97 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox