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FB:Nipped-B

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Nipped-B ( synonyms: CG17704, CG40281, NipB, Nipped, Nipped B, l(2)02047, nipped-B )
Protein Name(s) Nipped-B,
External Links
FB FBgn0026401

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007064

mitotic sister chromatid cohesion

FB:FBrf0174962
PMID:15060134[1]

IMP: Inferred from Mutant Phenotype

P

From FB

complete

GO:0005634

nucleus

FB:FBrf0174962
PMID:15060134[1]

IDA: Inferred from Direct Assay

C

From FB

complete

GO:0003682

chromatin binding

FB:FBrf0203017
PMID:17965872[2]

IDA: Inferred from Direct Assay

F

See SF2952055 NTR: transcriptionally active chromatin binding. Or is this a cellular component?

complete

GO:0010628

positive regulation of gene expression

FB:FBrf0203143
PMID:17909832[3]

IMP: Inferred from Mutant Phenotype

P

From FB

complete

GO:0007064

mitotic sister chromatid cohesion

FB:FBrf0203143
PMID:17909832[3]

IMP: Inferred from Mutant Phenotype

P

From FB

complete

GO:0043234

protein complex

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

complete

Colocalizes with

GO:0000795

synaptonemal complex

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

complete

Colocalizes with

GO:0008278

cohesin complex

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

complete

GO:0005634

nucleus

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

complete

GO:0010628

positive regulation of gene expression

FB:FBrf0205879
PMID:18713858[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0004644


P

From FB

complete

GO:0045893

positive regulation of transcription, DNA-dependent

FB:FBrf0109032
PMID:10353901[5]

IMP: Inferred from Mutant Phenotype

P

SF 2952117 NTR: long-range enhancer-promoter communication

complete

GO:0005488

binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011989
InterPro:IPR016024

F

From FB

GO:0005634

nucleus

FB:FBrf0174962
PMID:15060134[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005654

nucleoplasm

FB:FBrf0211896
PMID:20696838[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0174962
PMID:15060134[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007064

mitotic sister chromatid cohesion

FB:FBrf0174962
PMID:15060134[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007064

mitotic sister chromatid cohesion

FB:FBrf0203143
PMID:17909832[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010628

positive regulation of gene expression

FB:FBrf0203143
PMID:17909832[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010628

positive regulation of gene expression

FB:FBrf0205879
PMID:18713858[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0004644

P

From FB

GO:0035327

transcriptionally active chromatin

FB:FBrf0203017
PMID:17965872[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0043234

protein complex

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0070193

synaptonemal complex organization

FB:FBrf0203143
PMID:17909832[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0071733

transcriptional activation by promoter-enhancer looping

FB:FBrf0109032
PMID:10353901[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0004198

P

From FB

colocalizes_with

GO:0000795

synaptonemal complex

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0008278

cohesin complex

FB:FBrf0203143
PMID:17909832[3]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0008278

cohesin complex

FB:FBrf0211896
PMID:20696838[6]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Rollins RA et al. (2004) Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene. Mol Cell Biol 24: 3100-11 PubMed GONUTS page
  2. 2.0 2.1 Misulovin Z et al. (2008) Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome. Chromosoma 117: 89-102 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 Gause M et al. (2008) Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells. Chromosoma 117: 51-66 PubMed GONUTS page
  4. 4.0 4.1 Hallson G et al. (2008) The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) protein. Proc Natl Acad Sci U S A 105: 12405-10 PubMed GONUTS page
  5. 5.0 5.1 Rollins RA et al. (1999) Nipped-B, a Drosophila homologue of chromosomal adherins, participates in activation by remote enhancers in the cut and Ultrabithorax genes. Genetics 152: 577-93 PubMed GONUTS page
  6. 6.0 6.1 Gause M et al. (2010) Dosage-sensitive regulation of cohesin chromosome binding and dynamics by Nipped-B, Pds5, and Wapl. Mol Cell Biol 30: 4940-51 PubMed GONUTS page
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