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FB:Nf1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Nf1 ( synonyms: CG8318, NF-1, NF1, Neurofibromatosis 1, Neurofibromatosis Factor 1, Neurofibromatosis-1, Neurofibromin, Nf-1, dNF1, neurofibromatosis 1, neurofibromatosis type 1, neurofibromin, nf1 ) | |
| Protein Name(s) | Neurofibromin 1, | |
| External Links | ||
| FB | FBgn0015269 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005099 |
Ras GTPase activator activity |
FB:FBrf0093751 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005099 |
Ras GTPase activator activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005488 |
binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005622 |
intracellular |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0006979 |
response to oxidative stress |
FB:FBrf0200172 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007265 |
Ras protein signal transduction |
FB:FBrf0138535 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001965 |
P |
From FB |
||
| GO:0007265 |
Ras protein signal transduction |
FB:FBrf0138535 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003205 |
P |
From FB |
||
| GO:0007614 |
short-term memory |
FB:FBrf0125468 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007614 |
short-term memory |
FB:FBrf0211411 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007616 |
long-term memory |
FB:FBrf0211411 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0200172 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008355 |
olfactory learning |
FB:FBrf0125468 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008355 |
olfactory learning |
FB:FBrf0211411 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009408 |
response to heat |
FB:FBrf0200172 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019933 |
cAMP-mediated signaling |
FB:FBrf0093751 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040014 |
regulation of multicellular organism growth |
FB:FBrf0093751 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0193208 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042066 |
perineurial glial growth |
FB:FBrf0138519 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0011230 |
P |
From FB |
||
| GO:0042066 |
perineurial glial growth |
FB:FBrf0138519 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0011603 |
P |
From FB |
||
| GO:0045475 |
locomotor rhythm |
FB:FBrf0138535 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045762 |
positive regulation of adenylate cyclase activity |
FB:FBrf0093486 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046578 |
regulation of Ras protein signal transduction |
FB:FBrf0193208 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 The I et al. (1997) Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science 276: 791-4 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Tong JJ et al. (2007) Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila melanogaster. Nat Genet 39: 476-85 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Williams JA et al. (2001) A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK. Science 293: 2251-6 PubMed GONUTS page
- ↑ 4.0 4.1 Guo HF et al. (2000) A neurofibromatosis-1-regulated pathway is required for learning in Drosophila. Nature 403: 895-8 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Buchanan ME & Davis RL (2010) A distinct set of Drosophila brain neurons required for neurofibromatosis type 1-dependent learning and memory. J Neurosci 30: 10135-43 PubMed GONUTS page
- ↑ 6.0 6.1 Walker JA et al. (2006) Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons. Genes Dev 20: 3311-23 PubMed GONUTS page
- ↑ 7.0 7.1 Yager J et al. (2001) Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways. Proc Natl Acad Sci U S A 98: 10445-50 PubMed GONUTS page
- ↑ Guo HF et al. (1997) Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides. Science 276: 795-8 PubMed GONUTS page
